Shmueli Amir, Nissan-Englcin Esti
The Hebrew University.
Harefuah. 2008 Jun;147(6):488-92, 576.
The Public Committee bases its choices on clinical, ethical and social considerations, and not, in general, on the (minimal) cost per Quality Adjusted Life Year (QALY) of the technologies.
To examine the Public Committee's 2006/7 decisions from an economic viewpoint.
The examination analyzes the findings from reviews of: 1) Recent studies which estimated the Value of Statistical Life (VSL), and hence the value of QALY, in Israel and abroad, and 2) Reports of the costs per QALY of the technologies adopted.
The paper recommends that the Israeli willingness to pay (WTP) for human life is set at NIS 10 million, for life year at NIS 200,000 and for QALY at NIS 250,000. While the Committee's ranking of the 40 technologies, on which data was found, does not match the ranking by cost per QALY, the cost per QALY of all but three (Avastin, Myozyme and Zomera) was below NIS 250,000, and of most of the technologies was below NIS 150,000. Apart from these cases--which can be argued for on social-ethical-political specific grounds--the costs per QALY are below the WTP. In order to achieve an efficient and equitable allocation of national resources to areas which improve safety and health, the social WTP for life and for QALY must be seriously and publicly discussed.
公共委员会的决策基于临床、伦理和社会因素,一般并非基于技术的(最低)每质量调整生命年(QALY)成本。
从经济角度审视公共委员会2006/7年度的决策。
该审视分析了以下方面的审查结果:1)近期估计以色列国内外统计生命价值(VSL)以及QALY价值的研究;2)所采用技术的每QALY成本报告。
本文建议将以色列对人类生命的支付意愿设定为1000万新谢克尔,对生命年设定为20万新谢克尔,对QALY设定为25万新谢克尔。虽然委员会对找到数据的40种技术的排名与每QALY成本的排名不匹配,但除了三种技术(阿瓦斯汀、美而赞和佐米曲普坦)外,所有技术的每QALY成本均低于25万新谢克尔,且大多数技术的每QALY成本低于15万新谢克尔。除了这些可基于特定社会伦理政治理由进行论证的情况外,每QALY成本低于支付意愿。为了实现国家资源向改善安全和健康领域的高效公平分配,必须认真且公开地讨论社会对生命和QALY的支付意愿。