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冠状动脉痉挛:术后心肌梗死的一种罕见但重要的病因。

Coronary artery spasm: a rare but important cause of postoperative myocardial infarction.

作者信息

Guo Linrui Ray, Myers Mary Lee, Kuntz Eva L

机构信息

Division of Cardiac Surgery, London Health Science Centre, London, Ontario, Canada.

出版信息

Ann Thorac Surg. 2008 Sep;86(3):994-5. doi: 10.1016/j.athoracsur.2008.02.094.

Abstract

Myocardial infarction that is attributed to native coronary artery spasm in the early postoperative phase has rarely been documented. We report three cases of postoperative myocardial infarction secondary to angiographically demonstrated coronary spasm. Native coronary artery spasm is a rare, but important cause of postoperative ischemia and infarction. Suspicious electrocardiographic changes warrant consideration of transesophageal echocardiography to detect unexpected wall motion abnormalities. Established treatments include intravenous or intracoronary infusion of nitroglycerin and calcium channel antagonists, although several new therapeutic agents may also be beneficial. Prompt coronary angiography is the only definitive modality for early diagnosis and targeted treatment.

摘要

术后早期归因于原发性冠状动脉痉挛的心肌梗死鲜有文献记载。我们报告3例经血管造影证实为冠状动脉痉挛继发的术后心肌梗死病例。原发性冠状动脉痉挛是术后缺血和梗死的一个罕见但重要的原因。可疑的心电图变化值得考虑行经食管超声心动图检查以检测意外的室壁运动异常。既定的治疗方法包括静脉或冠状动脉内输注硝酸甘油和钙通道拮抗剂,尽管几种新的治疗药物可能也有益处。及时进行冠状动脉造影是早期诊断和靶向治疗的唯一确切方法。

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