基底细胞癌中表皮基底膜的免疫组织化学研究
The epidermal basement membrane in basal cell carcinoma: an immunohistochemical study.
作者信息
Markey A C, Tidman M J, Churchill L J, Aplin J D, Leigh I M, Purkis P, MacDonald D M
机构信息
Laboratory of Applied Dermatopathology, UMDS, London, U.K.
出版信息
Br J Dermatol. 1991 Jul;125(1):21-6. doi: 10.1111/j.1365-2133.1991.tb06033.x.
Abstract
An immunohistochemical study of basal cell carcinomas of varying histological type, using a panel of antibodies to constituents of the epidermal basement membrane, showed marked deficiencies in the expression of the antigens identified by the antibodies LH7.2, GB3 and G71. There was no correlation between loss of immunoreactivity to these antibodies and the histological features of the tumour.
摘要
一项使用一组针对表皮基底膜成分的抗体，对不同组织学类型的基底细胞癌进行的免疫组织化学研究显示，由抗体LH7.2、GB3和G71识别的抗原表达存在明显缺陷。对这些抗体免疫反应性的丧失与肿瘤的组织学特征之间没有相关性。
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