[Oral and maxillofacial multiple primary cancers].

Among 2989 patients with oral and maxillofacial cancers treated in our department from 1953 to 1985, 49 cases (1.63%) had the multiple primary lesions. The double primary cancers occurred in 44 cases (89.8%), three or more in 5 cases (10.2%). The multiple foci in an organ happened in 16 cases, different organ of systems in 23, and two systems in 10 cases. The followup in 49 cases (92.4%) for 3-27 years revealed the survival rates as follow: 76% (3 yrs), 69% (5 yrs), 42% (10 yrs), and 33% (15 yrs). The aggressive surgical intervention should be performed in oral and maxillofacial multiple primary cancers for a good therapeutic result.