Yang Zhi-lin, Ke Yi-quan, Xu Ru-xiang, Peng Ping
Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(8):1460-2.
To evaluate the perfusion characteristics of the peritumoral brain edema of intracranial meningiomas using 16-slice spiral CT perfusion imaging.
Dynamic contrast-enhanced single-location sequence CT scan was performed in 19 patients with intracranial meningiomas and peritumoral brain edema. The regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV) and the mean transit time (MTT) were calculated for the peritumoral brain edema and the contralateral white matter and comparatively analyzed.
The rCBF and rCBV in the peritumoral brain edema were significantly lower than those of the contralateral white matter in patients with meningiomas (rCBF: 14.26-/+7.44 vs 26.92-/+15.71 ml/100 g tissue.min, P<0.05; rCBV: 0.96-/+0.35 vs 2.47-/+1.69 ml/100 g tissue, P<0.05). But the MTT showed no significant difference between the peritumoral brain edema and the contralateral white matter (P>0.05).
The rCBF and rCBV are significantly lowered in the peritumoral brain edema in comparison with those of the contralateral white matter. Vascular compression by the edema fluid may have a major effect on the tissue blood flow and blood volume.
采用16层螺旋CT灌注成像评估颅内脑膜瘤瘤周脑水肿的灌注特征。
对19例颅内脑膜瘤伴瘤周脑水肿患者进行动态对比增强单层面序列CT扫描。计算瘤周脑水肿及对侧白质的局部脑血流量（rCBF）、局部脑血容量（rCBV）和平均通过时间（MTT），并进行对比分析。
脑膜瘤患者瘤周脑水肿的rCBF和rCBV显著低于对侧白质（rCBF：14.26±7.44 vs 26.92±15.71 ml/100 g组织·min，P<0.05；rCBV：0.96±0.35 vs 2.47±1.69 ml/100 g组织，P<0.05）。但瘤周脑水肿与对侧白质的MTT差异无统计学意义（P>0.05）。
与对侧白质相比，瘤周脑水肿的rCBF和rCBV显著降低。水肿液对血管的压迫可能对组织血流量和血容量有重要影响。
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