Lane R S, Brown R N
Department of Entomological Sciences, University of California, Berkeley 94720.
J Med Entomol. 1991 May;28(3):299-302. doi: 10.1093/jmedent/28.3.299.
The etiologic agent of Lyme disease, Borrelia burgdorferi Johnson, Schmid, Hyde, Steigerwalt & Brenner, was isolated repeatedly from dusky-footed wood rats, Neotoma fuscipes Baird, and California kangaroo rats, Dipodomys californicus Merriam, in northern California. All animals were collected in a region endemic for Lyme disease but for which the natural reservoir of B. burgdorferi was unknown. Similar attempts to isolate spirochetes from lizards, other species of rodents, jack rabbits, and deer between 1987 and 1991 were unsuccessful. Spirochetes isolated from wood rats and kangaroo rats were antigenically similar to strains of B. burgdorferi that had been isolated previously from the western black-legged tick, Ixodes pacificus Cooley & Kohls, in California. Similar enzootic cycles involving wood rats or kangaroo rats should be sought in other regions of the United States where the reservoirs of this spirochete are unknown.
莱姆病的病原体——伯氏疏螺旋体（Borrelia burgdorferi Johnson, Schmid, Hyde, Steigerwalt & Brenner），在加利福尼亚北部的暗足林鼠（Neotoma fuscipes Baird）和加州更格卢鼠（Dipodomys californicus Merriam）中被反复分离出来。所有动物均采自莱姆病的地方流行区，但伯氏疏螺旋体的自然宿主尚不清楚。在1987年至1991年间，从蜥蜴、其他啮齿动物、长耳大野兔和鹿中分离螺旋体的类似尝试均未成功。从林鼠和更格卢鼠中分离出的螺旋体在抗原性上与之前从加利福尼亚的太平洋硬蜱（Ixodes pacificus Cooley & Kohls）中分离出的伯氏疏螺旋体菌株相似。在美国其他该螺旋体宿主尚不清楚的地区，应寻找涉及林鼠或更格卢鼠的类似动物流行病循环。
