Tsimmerman Ia S
Klin Med (Mosk). 1991 Feb;69(2):99-104.
Potentialities of current chemotherapy of chronic pancreatitis are delineated. An individual approach is advocated for patients with the primary and secondary disease varying in etiology, for those with and without external and internal pancreatic insufficiency. Indications are validated for application of drugs distinct from each other by mechanism of action and intended for pain relief, of kallikrein-protease and other trypsin inhibitors, replacement polyenzymatic therapy, stimulators of pancreatic exocrine secretion, antihistamine drugs, parenteral feeding, vitamins, detoxicating, immunomodulating and psychopharmacological agents. Approaches to management of chronic pancreatitis and its complications as well as associated diseases are detailed. Chronic pancreatitis sufferers must be followed up and undergo prophylactic treatment.
阐述了慢性胰腺炎当前化疗的潜力。对于病因各异的原发性和继发性疾病患者,以及有和没有胰腺内、外分泌功能不全的患者,提倡采用个体化治疗方法。验证了不同作用机制、用于缓解疼痛的药物、激肽释放酶 - 蛋白酶和其他胰蛋白酶抑制剂、替代多酶疗法、胰腺外分泌刺激剂、抗组胺药、肠外营养、维生素、解毒剂、免疫调节剂和精神药物的应用指征。详细介绍了慢性胰腺炎及其并发症以及相关疾病的管理方法。慢性胰腺炎患者必须接受随访并进行预防性治疗。