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p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.
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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy.
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Delayed ageing through damage protection by the Arf/p53 pathway.
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The two TORCs and Akt.
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Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.
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TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth.
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Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways.
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The antioxidant function of the p53 tumor suppressor.
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Upstream and downstream of mTOR.
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Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD.
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