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不进行即时甲状旁腺激素检测或放射性引导的锝[99mTc] 甲氧基异丁基异腈扫描的甲状旁腺手术。

Parathyroid surgery without instant PTH or radioguided Sestamibi scan.

作者信息

Vázquez-Quintana E, Vázquez-Torres D E

机构信息

Department of Surgery, Pavia Hospital, San Juan, PR.

出版信息

Bol Asoc Med P R. 2008 Jan-Mar;100(1):34-7.

Abstract

BACKGROUND

Radioguided Sestamibi scan and instant PTH (iPTH) are being used in minimally invasive parathyroid surgery (MIP). Experienced surgeons cure over 90-95% of the patients with primary hyperparathyroidism.

PURPOSE/METHOD: To study the surgical results in treating hyperparathyroidism in a for profit community hospital lacking both iPTH and radioguided Sestamibi scan, we reviewed the patients operated from November 1, 2005 to October 31, 2006.

RESULTS

The study comprised 56 patients: 52 with primary hyper-parathyroidism, three with secondary hyperparathyroidism and one with tertiary hyperparathyroidism. The only localizing test utilized pre-operatively was the Sestamibi Scan. PTH was measured immediately before and after surgery but the results was received seven to ten days later. The affected glands were removed in all patients. Fifty of 52 (96%) of the patients with primary hyperparathyroidism, the three patients with secondary hyper-parathyroidism and the patient with tertiary hyperparathyroidism are normocalcemic with normal PTH levels. Two patients have persistent mild hypercalcemia. Associated conditions were three papillary carcinoma of the thyroid, three multinodular goiter, four had a single thyroid nodule, one had an adrenal tumor and three were reoperations.

CONCLUSION

Parathyroid surgery can be done safely and effectively in community hospitals without the utilization of radioguided Sestamibi scan and iPTH measurement.

摘要

背景

放射性引导的甲氧基异丁基异腈扫描和即时甲状旁腺激素(iPTH)正用于微创甲状旁腺手术(MIP)。经验丰富的外科医生能治愈90%至95%以上的原发性甲状旁腺功能亢进患者。

目的/方法:为研究在一家既没有iPTH也没有放射性引导的甲氧基异丁基异腈扫描的营利性社区医院中治疗甲状旁腺功能亢进的手术结果,我们回顾了2005年11月1日至2006年10月31日期间接受手术的患者。

结果

该研究包括56例患者:52例原发性甲状旁腺功能亢进,3例继发性甲状旁腺功能亢进和1例三发性甲状旁腺功能亢进。术前唯一使用的定位检查是甲氧基异丁基异腈扫描。在手术前后立即测量甲状旁腺激素,但结果在七至十天后才收到。所有患者均切除了受影响的腺体。52例原发性甲状旁腺功能亢进患者中的50例(96%)、3例继发性甲状旁腺功能亢进患者和1例三发性甲状旁腺功能亢进患者血钙正常,甲状旁腺激素水平正常。两名患者仍有持续性轻度高钙血症。相关病症包括3例甲状腺乳头状癌、3例结节性甲状腺肿、4例有单个甲状腺结节、1例有肾上腺肿瘤以及3例再次手术。

结论

在社区医院中,不使用放射性引导的甲氧基异丁基异腈扫描和甲状旁腺激素测量也能安全有效地进行甲状旁腺手术。

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