Amino acid variations at a single residue in an autoimmune peptide profoundly affect its properties: T-cell activation, major histocompatibility complex binding, and ability to block experimental allergic encephalomyelitis.
作者信息
Hood L, Horvath S J, Kumar V, Urban J L
出版信息
Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6899. doi: 10.1073/pnas.88.15.6899b.
Abstract
摘要
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Amino acid variations at a single residue in an autoimmune peptide profoundly affect its properties: T-cell activation, major histocompatibility complex binding, and ability to block experimental allergic encephalomyelitis.自身免疫肽中单个残基处的氨基酸变异会深刻影响其特性：T细胞活化、主要组织相容性复合体结合以及阻断实验性变应性脑脊髓炎的能力。
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本文引用的文献
1
Amino acid variations at a single residue in an autoimmune peptide profoundly affect its properties: T-cell activation, major histocompatibility complex binding, and ability to block experimental allergic encephalomyelitis.自身免疫肽中单个残基处的氨基酸变异会深刻影响其特性：T细胞激活、主要组织相容性复合体结合以及阻断实验性变应性脑脊髓炎的能力。
Proc Natl Acad Sci U S A. 1990 Feb;87(4):1337-41. doi: 10.1073/pnas.87.4.1337.
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