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腹腔镜根治性膀胱切除术联合原位胃新膀胱:技术与初步结果。

Laparoscopic radical cystectomy with orthotopic gastric neobladder: technique and initial outcomes.

作者信息

Wang Xing-Huan, Pu Xiao-Yong, Wang Huai-Peng, Hu Li-Quan

机构信息

Urology and Andrology Center, Zhongnan Hospital, Wuhan University, Number 169, Donghu Road, 430071, Wuhan, Hubei, China.

出版信息

J Cancer Res Clin Oncol. 2009 Feb;135(2):197-202. doi: 10.1007/s00432-008-0457-4. Epub 2008 Sep 3.

Abstract

OBJECTIVES

To report our operative technique and initial outcomes of laparoscopic radical cystectomy (LRC) and external orthoptic gastric neobladder.

METHODS

Since 2003, nine patients have undergone laparoscopic radical cystectomy with orthotopic gastric neobladder at our institution. The specimen is extracted through a 6-cm vertical minilaparotomy incision above the umbilicus. The gastric neobladder was constructed as our open technique using the part of stomach body and antrum with the pedicle of gastroepiploic vascular bundle through the site of specimen retrieval. The operative data, complications and follow-up functional data were analyzed.

RESULTS

The mean operative time was 365 min (300-450). Mean blood loss was 520 ml (200-1,500) and four patients (44.4%) required blood transfusion. In all cases no conversion to open surgery was necessary. The length of stay was 17 days and the total complication rate was 55.6% (five cases). All patients were free of recurrence at a mean follow-up of 22 months (3-48). The day and night incontinence rate was 11.1 and 44.4%, respectively. At 6 months after operation, urodynamic evaluations indicated a larger capacity, low pressure urinary reservoir.

CONCLUSIONS

Laparoscopic radical cystectomy with orthotopic gastric neobladder is a feasible intervention. The external construction of the gastric neobladder using the part of stomach body and antrum is quick and safe. With precise and increased operative technique, the LRC with orthotopic gastric bladder may be a good choice for urinary diversion. However, the larger samples, long-term compared studies with bowel diversions are required to evaluate this new technique.

摘要

目的

报告我们腹腔镜根治性膀胱切除术(LRC)及外置原位胃新膀胱的手术技术和初步结果。

方法

自2003年以来,我们机构有9例患者接受了腹腔镜根治性膀胱切除术并原位构建胃新膀胱。标本通过脐上一个6厘米的垂直小剖腹切口取出。胃新膀胱采用我们的开放技术构建,利用胃体和胃窦部分,通过标本取出部位带胃网膜血管束蒂。分析手术数据、并发症及随访功能数据。

结果

平均手术时间为365分钟(300 - 450分钟)。平均失血量为520毫升(200 - 1500毫升),4例患者(44.4%)需要输血。所有病例均无需转为开放手术。住院时间为17天,总并发症发生率为55.6%(5例)。平均随访22个月(3 - 48个月)时所有患者均无复发。日夜尿失禁率分别为11.1%和44.4%。术后6个月,尿动力学评估显示新膀胱容量更大、压力低。

结论

腹腔镜根治性膀胱切除术并原位胃新膀胱是一种可行的干预措施。利用胃体和胃窦部分外置构建胃新膀胱快速且安全。随着手术技术的精确化和提高,腹腔镜根治性膀胱切除术并原位胃新膀胱可能是尿流改道的一个良好选择。然而,需要更大样本、与肠代膀胱进行长期对比研究来评估这项新技术。

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