Kuwahar Yasuhito, Nishii Naohito, Takasu Masaki, Ohba Yasunori, Maeda Sadatoshi, Kitagawa Hitoshi
Kuwahara Animal Hospital, Moriyama-ku, nagoya, Japan.
J Vet Med Sci. 2008 Aug;70(8):865-7. doi: 10.1292/jvms.70.865.
The clinical utility of the urine albumin/creatinine ratio (UAC) using a simplified analyzer for estimation of proteinuria was studied in cats and dogs. Measurement results for diluted feline and canine albumin standard solutions showed linearity. Although conversion formulas (y=1.28x+1.04 and y=1.67x+10.47 for cats and dogs, respectively) were necessary, urine albumin concentrations could be determined in both animals. In cats and dogs with proteinuria, the UAC changed parallel with the urine protein/ creatinine ratio (UPC), and the Log UAC and Log UPC were significantly correlated (r=0.803 (p<0.01) in cats, r=0.801 (p<0.01) in dogs). The UAC using an UAC analyzer could be used clinically as one of the basic in-hospital laboratory tests for estimation of proteinuria in cats and dogs.
研究了使用简化分析仪测定的尿白蛋白/肌酐比值(UAC)在猫和狗中评估蛋白尿的临床实用性。稀释的猫和狗白蛋白标准溶液的测量结果呈线性。虽然需要转换公式(猫为y = 1.28x + 1.04,狗为y = 1.67x + 10.47),但两种动物的尿白蛋白浓度均可测定。在患有蛋白尿的猫和狗中,UAC与尿蛋白/肌酐比值(UPC)平行变化,并且Log UAC和Log UPC显著相关(猫中r = 0.803(p < 0.01),狗中r = 0.801(p < 0.01))。使用UAC分析仪测定的UAC可作为临床评估猫和狗蛋白尿的基本院内实验室检测之一。