药物和化学品自我中毒：人口统计学特征、相关因素及最终结局的差异

Self-poisoning by drugs and chemicals: variations in demographics, associated factors and final outcomes.

作者信息

Fathelrahman Ahmed Ibrahim, Ab Rahman Ab Fatah, Mohd Zain Zaininah

机构信息

National Poison Center, Universiti Sains Malaysia, Minden, USM Pulau Pinang 11800, Malaysia.

出版信息

Gen Hosp Psychiatry. 2008 Sep-Oct;30(5):467-70. doi: 10.1016/j.genhosppsych.2008.04.004. Epub 2008 Jul 23.

DOI:10.1016/j.genhosppsych.2008.04.004

PMID:18774431

Abstract

OBJECTIVE

Drug overdose exposures were compared with chemical poisoning in terms of demographics, associated factors and final outcomes.

METHOD

Deliberate self-poisoning (DSP) cases admitted to Penang General Hospital during the years 2000-2004 were studied. Chi-square, independent t-test and binary logistic were used whenever applicable.

RESULTS

Indian patients were more likely to use household products, whereas Malay and Chinese patients were more likely to take drug overdoses (P=.001). Drug overdose victims experienced more socioeconomic problems (P=.05) and were more likely to be admitted to the intensive care unit (P=.052). Chemical poisoning patients presented earlier (P=.011), were hospitalized for shorter time (P=.001) and had a higher rate of mortality (P=.01).

CONCLUSION

The present study has identified a unique ethnic variation in the choice of suicide attempts from toxic substances. DSP associated with drug overdose showed significant morbidity, but increased mortality was seen in chemical poisoning.

摘要

目的

从人口统计学、相关因素及最终结局方面对药物过量暴露与化学中毒进行比较。

方法

对2000年至2004年期间槟城总医院收治的蓄意自我中毒（DSP）病例进行研究。在适用时采用卡方检验、独立样本t检验和二元逻辑回归分析。

结果

印度患者更倾向于使用家用产品，而马来族和华裔患者更倾向于过量服药（P = 0.001）。药物过量受害者面临更多社会经济问题（P = 0.05），且更有可能入住重症监护病房（P = 0.052）。化学中毒患者就诊更早（P = 0.011），住院时间更短（P = 0.001），死亡率更高（P = 0.01）。