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容积旋转调强放疗治疗实施的剂量验证

Dosimetric verification of RapidArc treatment delivery.

作者信息

Korreman Stine, Medin Joakim, Kjaer-Kristoffersen Flemming

机构信息

Department of Radiation Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen O, Denmark.

出版信息

Acta Oncol. 2009;48(2):185-91. doi: 10.1080/02841860802287116.

Abstract

PURPOSE

Recently, Varian Medical Systems have announced the introduction of a new treatment technique, in which dose is delivered over a single gantry rotation with variable MLC positions, dose rate and gantry speed. In February 2008, a preclinical installation of the RapidArc beam delivery approach was carried out on a Varian Clinac at Rigshospitalet in Copenhagen. The purpose of the installation was to perform measurements to verify the correctness of doses delivered with the RapidArc technique. In May 2008, the clinical release of the RapidArc application was installed at Rigshospitalet.

METHODS AND MATERIALS

Nine treatment plans were generated in the Eclipse version 8.5 including the RapidArc optimizer for H&N and prostate cases. The plans were delivered to the Scandidos Delta4 cylindrical diode array phantom. First, the measured dose distributions were compared with the calculated doses. All plans were then delivered several times to verify consistency of the delivery. Gamma analysis was used to verify the correspondence between dose distributions. The temporal resolution of the delivery was analysed by investigating the arc segments between control points separately.

RESULTS

Overall, good agreement was observed between measured and calculated doses in most cases with gamma values above 1 in >95% of measured points. The reproducibility of delivery was also very high. Gamma analysis between two consecutive runs of the same delivery plan generally showed gamma values above 1 in none of the measured points, and dose deviation less than 1%. Temporal analysis showed small discrepancies between doses delivered between control points (approximately 2 degrees of the rotation) in consecutive runs of a plan, however these were cancelled out in the accumulated dose.

CONCLUSION

The delivery of RapidArc beam delivery has been verified to correspond well with calculated dose distributions for a number of different cases. The delivery was very reproducible, and was carried out with high stability of the accelerator performance.

摘要

目的

最近,瓦里安医疗系统公司宣布推出一种新的治疗技术,该技术在单个机架旋转过程中通过可变的多叶准直器(MLC)位置、剂量率和机架速度来输送剂量。2008年2月,在哥本哈根里格霍斯医院的一台瓦里安直线加速器上对RapidArc束流输送方法进行了临床前安装。此次安装的目的是进行测量,以验证使用RapidArc技术输送剂量的正确性。2008年5月,RapidArc应用的临床版本在里格霍斯医院安装。

方法和材料

在Eclipse 8.5版本中生成了9个治疗计划,包括用于头颈部和前列腺病例的RapidArc优化器。这些计划被输送到Scandidos Delta4圆柱形二极管阵列模体。首先,将测量的剂量分布与计算剂量进行比较。然后所有计划都被多次输送以验证输送的一致性。使用伽马分析来验证剂量分布之间的对应关系。通过分别研究控制点之间的弧形段来分析输送的时间分辨率。

结果

总体而言,在大多数情况下,测量剂量与计算剂量之间观察到良好的一致性,超过95%的测量点伽马值大于1。输送的可重复性也非常高。同一输送计划连续两次运行之间的伽马分析通常显示,在所有测量点中伽马值均不大于1,剂量偏差小于1%。时间分析表明,在计划的连续运行中,控制点之间(大约旋转2度)输送的剂量存在小的差异,然而这些差异在累积剂量中被抵消。

结论

已验证RapidArc束流输送在许多不同病例中与计算的剂量分布非常吻合。输送具有很高的可重复性,并且在加速器性能高度稳定的情况下进行。

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