Department of C-L Psychiatry, Paris 5 University, European Georges Pompidou Hospital, 20, rue Leblanc, 75908 Paris, France.
Int J Cardiol. 2010 Feb 4;138(3):277-80. doi: 10.1016/j.ijcard.2008.08.017. Epub 2008 Sep 11.
Erectile dysfunction (ED) is a frequent comorbid condition in men with coronary heart disease (CHD). Depressive mood is associated with adverse outcomes in CHD patients. The aim of this study was to explore the relationships between ED and depressive mood in CHD male patients.
Eighty-five CHD male patients were given standardized questionnaires to assess ED, depressive mood, current anxiety, and Type-D personality (i.e. negative affectivity and social inhibition).
A significant ED was found in 57.6% of the patients. Controlling for psychometric measures, CHD risk factors, and drugs, a significant ED was independently predicted by depressive mood, hypertension and, marginally, age.
These results confirm the high prevalence of ED in CHD male patients. They suggest that ED in CHD male patients may be more strongly associated with depressive mood than with antihypertensive drugs. Because depressive mood is associated with adverse CHD outcomes and may require adequate treatment, clinicians should better search for depressive mood in CHD patients presenting with ED.
勃起功能障碍（ED）是冠心病（CHD）男性患者常见的合并症。抑郁情绪与 CHD 患者的不良预后相关。本研究旨在探讨 CHD 男性患者中 ED 和抑郁情绪之间的关系。
85 名 CHD 男性患者接受了标准化问卷评估，以评估 ED、抑郁情绪、当前焦虑和 Type-D 人格（即负性情感和社交抑制）。
在 57.6%的患者中发现存在明显的 ED。控制心理测量指标、CHD 危险因素和药物后，抑郁情绪、高血压以及年龄（勉强）可独立预测 ED。
这些结果证实了 CHD 男性患者中 ED 的高患病率。它们表明，CHD 男性患者的 ED 可能与抑郁情绪的相关性强于与降压药物的相关性。由于抑郁情绪与不良的 CHD 结局相关，可能需要适当治疗，因此临床医生在出现 ED 的 CHD 患者中应更好地寻找抑郁情绪。
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