碳水化合物微阵列作为研究碳水化合物介导的生物过程的强大工具。
Carbohydrate microarrays as powerful tools in studies of carbohydrate-mediated biological processes.
作者信息
Park Sungjin, Lee Myung-Ryul, Shin Injae
机构信息
Department of Chemistry, Yonsei University, Seoul, 120-749, South Korea.
出版信息
Chem Commun (Camb). 2008 Oct 7(37):4389-99. doi: 10.1039/b806699j. Epub 2008 Jul 28.
Carbohydrate microarrays have become very powerful tools to elucidate the molecular basis of carbohydrate-recognition events in a high-throughput manner. This microarray technology has been applied in the rapid analysis of the binding properties of a variety of binding partners such as lectins, antibodies, mammalian cells, pathogens and viruses. In this feature article, methods for the preparation of carbohydrate microarrays and their applications in biological and biomedical research are described.
碳水化合物微阵列已成为以高通量方式阐明碳水化合物识别事件分子基础的非常强大的工具。这种微阵列技术已应用于快速分析各种结合伴侣（如凝集素、抗体、哺乳动物细胞、病原体和病毒）的结合特性。在这篇专题文章中，描述了碳水化合物微阵列的制备方法及其在生物学和生物医学研究中的应用。
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