Zhang Yi-qun, Zhou Ping-hong, Xu Mei-dong, Zhong Yun-shi, Chen Wei-feng, Ma Li-li, Qin Wen-zheng, Cai Xian-li, Yao Li-qing
Department of Endoscopic Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Sep;11(5):421-3.
To evaluate the long-term efficacy of endoscopic excision for rectal carcinoids.
Clinical data of 91 patients with rectal carcinoids treated by endoscopic excision from 2000 to 2007 were analyzed retrospectively.
The average size of the primary tumor was 0.8 cm(range 0.3 to 2.3 cm). All the tumors were localized within the submucosal layer showing typical histology without lymphatic or vessel infiltration. Follow-up was available for 80 patients with mean 32.5 months (range 6 to 96 months). There was no recurrence in 65 patients with tumor size < 1.0 cm. Recurrence occurred in 3 cases among 25 patients with tumor size from 1.0 to 2.0 cm, and 1 died of hepatic metastasis. The 1-, 3-, and 5-year survival rates of the patients were 100%, 98.0%, and 91.4% respectively.
Tumor size and depth of invasion are two important prognostic factors of rectal carcinoids. Endoscopic excision is useful for rectal carcinoid patients with tumor size < 1.0 cm and located within the submucosal layer.
评估内镜下切除直肠类癌的长期疗效。
回顾性分析2000年至2007年接受内镜下切除的91例直肠类癌患者的临床资料。
原发肿瘤平均大小为0.8 cm（范围0.3至2.3 cm）。所有肿瘤均局限于黏膜下层，组织学表现典型，无淋巴或血管浸润。80例患者获得随访，平均随访32.5个月（范围6至96个月）。肿瘤大小<1.0 cm的65例患者无复发。肿瘤大小为1.0至2.0 cm的25例患者中有3例复发，1例死于肝转移。患者的1年、3年和5年生存率分别为100%、98.0%和91.4%。
肿瘤大小和浸润深度是直肠类癌的两个重要预后因素。内镜下切除对肿瘤大小<1.0 cm且位于黏膜下层的直肠类癌患者有用。
