尼古丁依赖、心理困扰和人格特质作为戒烟的可能预测因素。一项使用尼古丁贴片的双盲研究结果。

Nicotine dependence, psychological distress and personality traits as possible predictors of smoking cessation. Results of a double-blind study with nicotine patch.

作者信息

Cosci Fiammetta, Corlando Annalisa, Fornai Edo, Pistelli Francesco, Paoletti Paolo, Carrozzi Laura

机构信息

Maastricht University, Department of Psychiatry and Neuropsychology, PO Box 616 6200 MD Maastricht, The Netherlands.

出版信息

Addict Behav. 2009 Jan;34(1):28-35. doi: 10.1016/j.addbeh.2008.08.003. Epub 2008 Sep 19.

DOI:10.1016/j.addbeh.2008.08.003

PMID:18804918

Abstract

AIM

Nicotine replacement therapy (NRT) is an effective treatment for smokers who want to quit, however, the rates of successful quitting can be improved even more. In this context, nicotine dependence (assessed via the Fagerström Tolerance Questionnaire, FTQ), psychological distress (measured via the Symptom Rating Test, SRT), and personality traits (evaluated via the Adult Eysenck Personality Inventory, AEPI) were evaluated as possible predictors of smoking cessation.

RESULTS

A total of 297 cigarette smokers were followed for one year as part of a NRT double-blind, parallel group, randomized trial. Baseline nicotine dependence (weeks 12 and 26: p<0.05), AEPI neuroticism (weeks 12 and 52: p<0.05), and AEPI psychoticism (weeks 12 and 52: p<0.05) scores significantly influenced the outcome of smoking cessation during one-year of follow-up. An increase in psychological distress during follow-up was associated with a lower probability of quitting smoking (p=0.000).

CONCLUSIONS

Nicotine dependence, neuroticism, psychoticism and, over time, psychological distress were the main factors influencing the long-term outcome (i.e., up to 12 months) of smoking cessation under NRT.

摘要

目的

尼古丁替代疗法（NRT）是帮助有戒烟意愿的吸烟者的一种有效治疗方法，然而，成功戒烟率仍有提升空间。在此背景下，对尼古丁依赖（通过法格斯特罗姆耐受问卷，FTQ评估）、心理困扰（通过症状评定测试，SRT测量）以及人格特质（通过成人艾森克人格问卷，AEPI评估）进行评估，作为戒烟的可能预测因素。

结果

作为NRT双盲、平行组随机试验的一部分，共对297名吸烟者进行了为期一年的随访。基线尼古丁依赖（第12周和第26周：p<0.05）、AEPI神经质得分（第12周和第52周：p<0.05）以及AEPI精神质得分（第12周和第52周：p<0.05）在一年随访期间对戒烟结果有显著影响。随访期间心理困扰增加与戒烟可能性降低相关（p=0.000）。