眶内容剜出术后眶骨肥厚
Orbital hyperostosis following exenteration.
作者信息
Fleming James Chris, Linder James S, Karcioglu Zeynel A
机构信息
Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, Tennessee 38103, USA.
出版信息
Ophthalmic Plast Reconstr Surg. 2008 Sep-Oct;24(5):378-82. doi: 10.1097/IOP.0b013e3181832661.
PURPOSE
To report the development of unilateral, diffuse hyperostosis of orbital bones in 3 postexenteration patients.
METHODS
Three advanced cases of periorbital and orbital malignancies are presented, and their clinical, radiologic, and histopathologic features are reviewed.
RESULTS
Postexenteration CT showed thickened orbital walls in all 3 cases. The histopathology revealed necrotic destruction of the trabeculae mixed with randomly distributed chronic inflammatory cells and fibrosis and inflamed overlying granulation tissue.
CONCLUSION
The delayed healing of the granulation tissue during secondary intention in these cases is quite likely the cause of chronic osteitis of the underlying orbital bone that, in turn, led to postoperative diffuse hyperostosis.
目的
报告3例眼眶内容剜除术后患者单侧眼眶骨弥漫性骨质增生的发生情况。
方法
介绍3例晚期眶周及眼眶恶性肿瘤病例，并回顾其临床、放射学和组织病理学特征。
结果
眼眶内容剜除术后CT显示所有3例患者眼眶壁增厚。组织病理学显示小梁坏死性破坏，伴有随机分布的慢性炎症细胞和纤维化，以及覆盖其上的炎性肉芽组织。
结论
这些病例二期愈合过程中肉芽组织延迟愈合很可能是导致其下方眼眶骨慢性骨炎的原因，进而导致术后弥漫性骨质增生。
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