Spadavecchia C, Jaggy A
Department of Clinical Veterinary Medicine University of Berne, Switzerlnad.
Schweiz Arch Tierheilkd. 2008 Oct;150(10):515-8. doi: 10.1024/0036-7281.150.10.515.
An 8 years old male persian cat with a diagnosis of myasthenia gravis was scheduled for transternal thoracotomy. An anterior mediastinal mass, suspected to be a thymoma, had to be resected. Progressive paraparesis and reduced ocular reflexes and menace response were the main clinical features. At the preoperative examination the cat appeared free of significant myocardial or respiratory diseases. The possibility of compromised respiratory function due to muscle weakness was addressed by the choice of a balanced anesthesia protocol without the use of muscle-relaxants. Intravenous induction was followed by intubation, administration of isoflurane in oxygen and ventilatory support. Thorough cardiorespiratory monitoring was performed during anaesthesia. Epidural morphin was given to reduce the amount of inhalation agent required to maintain anaesthesia and supplemental intravenous analgesia was given. At the end of the surgery, intrapleural bupivacaine was administered to help controlling poststernotomy pain, while reducing the need for systemic analgesics. Although rapid returning of swallowing reflex and spontaneous breathing followed the disconnection from the anaesthetic circuit, the cat needed to breath oxygen enriched air to maintain a normal hemoglobin saturation in the early postoperative phase.
一只8岁的雄性波斯猫被诊断为重症肌无力,计划进行经胸骨开胸手术。必须切除一个怀疑为胸腺瘤的前纵隔肿块。进行性截瘫、眼反射减弱和威胁反应减弱是主要临床特征。术前检查时,这只猫似乎没有明显的心肌或呼吸系统疾病。由于选择了不使用肌肉松弛剂的平衡麻醉方案,解决了因肌肉无力导致呼吸功能受损的可能性。静脉诱导后进行插管,在氧气中给予异氟烷并进行通气支持。麻醉期间进行了全面的心肺监测。给予硬膜外吗啡以减少维持麻醉所需的吸入剂用量,并给予补充静脉镇痛。手术结束时,给予胸膜内布比卡因以帮助控制胸骨切开术后疼痛,同时减少对全身镇痛药的需求。尽管从麻醉回路断开后吞咽反射和自主呼吸迅速恢复,但这只猫在术后早期需要呼吸富氧空气以维持正常的血红蛋白饱和度。