诊断血液病理学中的陷阱：第一部分。
Pitfalls in diagnostic hematopathology: part I.
作者信息
Zhao Xianfeng F
机构信息
Department of Pathology, University of Maryland School of Medicine Baltimore, MD, USA.
出版信息
Int J Clin Exp Pathol. 2009;2(1):11-20. Epub 2008 Apr 21.
Abstract
Pitfalls in diagnostic hematopathology are underestimated and underreported. Major causes of diagnostic error in hematopathology include: 1) inadequate material; 2) inadequate workup; 3) inadequate clinical correlation; 4) over or under interpretation; 5) challenges in hematopathology. In the first part of this review series, I will focus on the pitfalls in diagnosing and differentiating chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma, and discuss the strategies to avoid potential diagnostic errors based on my personal experience.
摘要
血液病理学诊断中的陷阱常被低估且报告不足。血液病理学诊断错误的主要原因包括：1）样本不足；2）检查不充分；3）临床关联不足；4）解读过度或不足；5）血液病理学中的挑战。在本综述系列的第一部分，我将重点关注慢性淋巴细胞白血病/小淋巴细胞淋巴瘤（CLL/SLL）和套细胞淋巴瘤诊断与鉴别中的陷阱，并根据我的个人经验讨论避免潜在诊断错误的策略。
相似文献
1
Pitfalls in diagnostic hematopathology: part I.
Int J Clin Exp Pathol. 2009;2(1):11-20. Epub 2008 Apr 21.
2
Value of CD23 determination by flow cytometry in differentiating mantle cell lymphoma from chronic lymphocytic leukemia/small lymphocytic lymphoma.
Am J Clin Pathol. 2001 Dec;116(6):893-7. doi: 10.1309/UQ4N-M5KL-0ANY-YD3G.
3
4
Primary manifestation of small lymphocytic lymphoma in the prostate.
Onkologie. 2009 Oct;32(10):586-8. doi: 10.1159/000232584. Epub 2009 Sep 11.
5
Distinction between small lymphocytic and mantle cell lymphoma by immunoreactivity for CD23.
Mod Pathol. 1994 Apr;7(3):326-31.
6
7
Incidence of phenotypic aberrations in a series of 467 patients with B chronic lymphoproliferative disorders: basis for the design of specific four-color stainings to be used for minimal residual disease investigation.
Leukemia. 2002 Aug;16(8):1460-9. doi: 10.1038/sj.leu.2402584.
8
Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia.
Hum Pathol. 2008 Jul;39(7):1050-8. doi: 10.1016/j.humpath.2007.11.012. Epub 2008 May 13.
9
Autoimmune cytopenia does not predict poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma.
Am J Hematol. 2003 Sep;74(1):1-8. doi: 10.1002/ajh.10369.
10
Small lymphocytic lymphoma and chronic lymphocytic leukemia: are they the same disease?
Cancer J. 2012 Sep-Oct;18(5):396-403. doi: 10.1097/PPO.0b013e31826cda2d.
引用本文的文献
1
CD5-negative mantle cell lymphoma: clinicopathologic features of an indolent variant that confers a survival advantage.
Leuk Lymphoma. 2022 Apr;63(4):911-917. doi: 10.1080/10428194.2021.2002317. Epub 2021 Nov 15.
2
Two cases of systemic mantle cell lymphoma involving the skin.
Indian Dermatol Online J. 2016 Jan-Feb;7(1):49-52. doi: 10.4103/2229-5178.174317.
3
Small lymphocytic lymphoma with florid perniosis-like features: a case report.
BMC Dermatol. 2015 Jul 23;15:11. doi: 10.1186/s12895-015-0032-z.
4
Diagnostic testing managed by hematopathology specialty and other laboratories: costs and patient diagnostic outcomes.
BMC Clin Pathol. 2014 Apr 27;14:17. doi: 10.1186/1472-6890-14-17. eCollection 2014.
5
Discordant lymphoma consisting of splenic mantle cell lymphoma and marginal zone lymphoma involving the bone marrow and peripheral blood: a case report.
J Med Case Rep. 2011 Sep 23;5:476. doi: 10.1186/1752-1947-5-476.
本文引用的文献
1
The cellular origin of mantle cell lymphoma.
Int J Biochem Cell Biol. 2007;39(10):1747-53. doi: 10.1016/j.biocel.2007.04.026. Epub 2007 May 10.
2
Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936.
Leukemia. 2007 Feb;21(2):207-14. doi: 10.1038/sj.leu.2404479. Epub 2006 Dec 14.
3
Gene-expression profiling of systemic anaplastic large-cell lymphoma reveals differences based on ALK status and two distinct morphologic ALK+ subtypes.
Blood. 2007 Mar 1;109(5):2156-64. doi: 10.1182/blood-2006-06-028969. Epub 2006 Oct 31.
4
Trisomy 12-associated, t(11;14)-negative mature B-cell leukemia with gene expression profile resembling mantle cell lymphoma.
Leuk Lymphoma. 2006 Jan;47(1):121-7. doi: 10.1080/10428190500259983.
5
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia.
N Engl J Med. 2005 Oct 27;353(17):1793-801. doi: 10.1056/NEJMoa050995.
6
Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling.
Blood. 2005 Dec 15;106(13):4315-21. doi: 10.1182/blood-2005-04-1753. Epub 2005 Aug 25.
7
Chronic lymphocytic leukemia/small lymphocytic lymphoma with trisomy 12 and focal cyclin d1 expression: a potential diagnostic pitfall.
Arch Pathol Lab Med. 2005 Jan;129(1):92-5. doi: 10.5858/2005-129-92-CLSLLW.
8
Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.
Blood. 2005 Jan 1;105(1):301-7. doi: 10.1182/blood-2004-06-2298. Epub 2004 Sep 2.
9
Proteomic analyses in Waldenstrom's macroglobulinemia and other plasma cell dyscrasias.
Semin Oncol. 2003 Apr;30(2):156-60. doi: 10.1053/sonc.2003.50066.
10
Biological and clinical heterogeneity of B-cell chronic lymphocytic leukemia.
Leuk Lymphoma. 2003 Feb;44(2):223-8. doi: 10.1080/1042819021000035756.
Zotero 插件