Martirosyan L, Braspenning J, Denig P, de Grauw W J C, Bouma M, Storms F, Haaijer-Ruskamp F M
Department of Clinical Pharmacology, University Medical Centre Groningen, University of Groningen, The Netherlands.
Qual Saf Health Care. 2008 Oct;17(5):318-23. doi: 10.1136/qshc.2007.024224.
Existing performance indicators for assessing quality of care in type 2 diabetes mellitus (T2DM) focus mostly on registration of measurements and clinical outcomes, and not on quality of prescribing.
To develop a set of valid prescribing quality indicators (PQI) for internal use in T2DM, and assess the operational validity of the PQI using electronic medical records.
Potential PQI for hypertension, hyperglycaemia, dyslipidaemia and antiplatelet treatment in T2DM were based on clinical guidelines, and assessed on face and content validity in an expert panel followed by a panel of GPs and diabetologists. Analysis of ratings was performed using the RAND/UCLA Appropriateness Method. The operational validity of selected indicators was assessed in a dataset of 3214 T2DM patients registered with 70 GPs.
Out of 31 potential prescribing indicators, the expert panel considered 18 indicators as sufficiently valid, of which 14 indicators remained valid after assessment by the panel of GPs and diabetologists. Of these 14 indicators, one could not be calculated because of an absence of eligible patients. For the remaining indicators, outcomes varied from 10% for timely prescribing of insulin to 96% for prescribing of any antihyperglycemic medication in patients with elevated HbA1c levels.
This study provides a set of face- and content-valid PQI for pharmacological management of patients with T2DM. While outcomes of some PQI were limited to patients with registration of clinical values, the selected PQI had good operational validity to be used in practice for assessment of prescribing quality.
现有的用于评估2型糖尿病(T2DM)护理质量的绩效指标大多侧重于测量结果和临床结局的记录,而非处方质量。
制定一套适用于T2DM内部使用的有效处方质量指标(PQI),并使用电子病历评估PQI的操作有效性。
基于临床指南确定T2DM中高血压、高血糖、血脂异常和抗血小板治疗的潜在PQI,并在专家小组以及随后的全科医生和糖尿病专家小组中进行表面效度和内容效度评估。使用RAND/UCLA适宜性方法对评分进行分析。在70名全科医生登记的3214例T2DM患者的数据集中评估所选指标的操作有效性。
在31个潜在的处方指标中,专家小组认为18个指标具有充分的有效性,其中14个指标在经过全科医生和糖尿病专家小组评估后仍然有效。在这14个指标中,有一个因缺乏符合条件的患者而无法计算。对于其余指标,结果从胰岛素及时处方率的10%到HbA1c水平升高患者中任何抗高血糖药物处方率的96%不等。
本研究为T2DM患者的药物治疗提供了一套表面效度和内容效度良好的PQI。虽然一些PQI的结果仅限于有临床值记录的患者,但所选的PQI在实践中用于评估处方质量具有良好的操作有效性。