Mohadjer M, Etou A, Milios E, Baden R, Mundinger F
Department of Neurosurgery, University of Freiburg, Federal Republic of Germany.
Neurochirurgia (Stuttg). 1991 May;34(3):90-3. doi: 10.1055/s-2008-1052062.
Optic nerve glioma is a rare tumor usually occurring in small children. How these tumors should be treated, is a matter of controversy. Recommended treatment ranges from a wait-and-see policy to radical excision with or without subsequent radio- or chemotherapy. Comparative data on these lesion are limited, as there are no randomized investigations and long-term studies reported in the literature. In 11 patients interstitial radiotherapy was carried out, by the implantation of J-125 seeds following confirmation of the histological diagnosis. The results are compared with those of 10 patients who underwent only biopsy for histological confirmation. CT-stereotactic biopsy to verify the diagnosis with subsequent interstitial irradiation is presented as an alternative therapy for optic gliomas.
视神经胶质瘤是一种罕见的肿瘤,通常发生于小儿。这些肿瘤应如何治疗,存在争议。推荐的治疗方法范围从观察等待策略到根治性切除,术后可进行或不进行放疗或化疗。关于这些病变的比较数据有限,因为文献中没有随机研究和长期研究报告。对11例患者进行了间质放疗,在组织学诊断确诊后植入碘-125种子。将结果与10例仅接受活检以进行组织学确诊的患者的结果进行比较。CT立体定向活检以确诊并随后进行间质照射被作为视神经胶质瘤的一种替代治疗方法。