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预测接种白血病细胞小鼠存活率的公式。

Formula predicting survival in mice inoculated with leukemia cells.

作者信息

Chung S J

机构信息

Department of Pathology, Morristown-Hamblen Hospital, Morristown, TN 37814.

出版信息

Int J Biomed Comput. 1991 May-Jun;28(1-2):31-45. doi: 10.1016/0020-7101(91)90024-9.

Abstract

A microcomputer program in BASIC for predicting the survival probability after inoculation of L1210 leukemia cells into mice is designed. Formulas used in this study are derived from the data published by Johnson et al. (J Natl Cancer Inst, 34 (1965) 277-290). A mathematical model and a computer program previously published by the author are employed in this study. Analysis of the computer-assisted predicted values and the reported data (J Natl Cancer Inst, 34 (1965) 277-290) on survival probabilities has shown that the program is accurate and reliable with a close agreement in expressing survival probability as a function of inoculum size and time after inoculation.

摘要

设计了一个用BASIC语言编写的微型计算机程序,用于预测将L1210白血病细胞接种到小鼠体内后的存活概率。本研究中使用的公式源自约翰逊等人发表的数据(《国家癌症研究所杂志》,34卷(1965年)277 - 290页)。本研究采用了作者先前发表的数学模型和计算机程序。对计算机辅助预测值与所报道的关于存活概率的数据(《国家癌症研究所杂志》,34卷(1965年)277 - 290页)进行分析表明,该程序准确可靠,在将存活概率表示为接种量和接种后时间的函数方面具有高度一致性。

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