Departments of Paediatric Otolaryngology and Radiology, Temple Street Children's Hospital, Dublin 1, Ireland.
Ir J Med Sci. 2010 Dec;179(4):611-3. doi: 10.1007/s11845-008-0221-4. Epub 2008 Oct 16.
Langerhans' cell histiocytosis (LCH) is a rare disorder of unknown aetiology, characterised by the proliferation of histiocytic cells in various tissues and organs. The role of the otolaryngologist is important in the early and accurate evaluation, staging and diagnosis of LCH, as it may mimic more common otological disorders.
We report the case of a 2-year-old child presenting with LCH and review the literature concerning this rare disease.
Presentation in our case was with a common aural polyp, refractory to medical treatment, which when biopsied, revealed LCH. Radiological evaluation showed multifocal disease.
A sound knowledge of the disease process in vital to the otolaryngologist, thus enabling rapid diagnosis and early treatment for a commonly fatal condition.
朗格汉斯细胞组织细胞增生症（LCH）是一种病因不明的罕见疾病，其特征是组织细胞在各种组织和器官中增殖。耳鼻喉科医生在早期准确评估、分期和诊断 LCH 方面发挥着重要作用，因为它可能模仿更常见的耳科疾病。
我们报告了一例 2 岁儿童患有 LCH 的病例，并回顾了有关这种罕见疾病的文献。
本例表现为常见的耳息肉，对药物治疗有抗药性，活检显示为 LCH。影像学评估显示多灶性疾病。
耳鼻喉科医生需要对疾病过程有深入的了解，以便快速诊断和早期治疗这种常见的致命疾病。
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