[定量交感神经切除术对幼鼠甲状腺C细胞和肾上腺嗜铬细胞适应性补偿反应发育的影响]
[Effects of dosed sympathectomy on the development of adaptation-compensation reaction of C-cells of the thyroid gland and chromaffin cells of the adrenal glands in young rats].
作者信息
Riashchikov S N, Markov V N, Glumova V A, Murashova M Iu, Elkin A S, Afanas'ev D A, Bazhenov A N, Marizin S A
出版信息
Biull Eksp Biol Med. 1991 Jun;111(6):663-6.
Using radioimmunological, morphometrical, electron microscopic and luminescent methods, comparative analysis of thyroid C-cells and adrenal chromaffin cells has been carried out at guanethidine sympathectomy in young rats. Significant decrease of functional activity of C-cells with concomitant hyperplasia of C-cells population under blockade of sympathetic influences has been revealed. Compared to C-cells, adrenal chromaffinocytes of sympathectomized rats possess higher degree of structural-functional mobilization and are characterized by intensive secretion of catecholamines directed at restoration of tissue neurotransmitter deficit.
运用放射免疫、形态计量、电子显微镜及发光方法，对年轻大鼠进行胍乙啶交感神经切除术后的甲状腺C细胞和肾上腺嗜铬细胞进行了比较分析。结果显示，在交感神经影响被阻断的情况下，C细胞功能活性显著降低，同时C细胞群体增生。与C细胞相比，交感神经切除大鼠的肾上腺嗜铬细胞具有更高程度的结构 - 功能动员，其特征是儿茶酚胺大量分泌，旨在恢复组织神经递质缺乏。
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