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胃十二指肠结核所致胃出口梗阻的外科治疗

Surgical treatment of gastric outlet obstruction due to gastroduodenal tuberculosis.

作者信息

Manzelli Antonio, Stolfi Vito M, Spina Claudio, Rossi Piero, Federico Francesco, Canale Silvia, Gaspari Achille L

机构信息

Department of Surgery, General Surgery Division, Policlinico Tor Vergata, University of Rome Tor Vergata, V le Oxford, 81 00133, Rome, Italy.

出版信息

J Infect Chemother. 2008 Oct;14(5):371-3. doi: 10.1007/s10156-008-0635-y. Epub 2008 Oct 21.

Abstract

Gastroduodenal tuberculosis is a very rare location of abdominal tuberculosis; it is usually secondary to pulmonary tuberculosis and is often associated with HIV infection. We report a case of a 45-year-old woman with no HIV infection and no evidence of pulmonary tuberculosis, with a history of duodenal ulcer treated for several months, who presented at the emergency department with severe gastric outlet obstruction of recent onset caused by ulcerohypertrophic antroduodenal tuberculosis. The lesion was misdiagnosed at endoscopy as a malignancy, although histological examination of biopsies showed only chronic inflammation. The diagnosis was established at surgery, when a frozen section of an enlarged lymph node showed the presence of giant cells and caseating granuloma. The treatment was gastric resection with Roux-en-Y gastrojejunal anastomosis. In this patient the rare gastroduodenal location of tuberculosis occurred as primary disease in the absence of other organ involvement.

摘要

胃十二指肠结核是腹部结核非常罕见的发病部位;它通常继发于肺结核,且常与HIV感染相关。我们报告一例45岁女性病例,该患者无HIV感染且无肺结核证据,有十二指肠溃疡病史并接受了数月治疗,因溃疡肥厚性胃十二指肠结核导致近期突发严重胃出口梗阻而就诊于急诊科。内镜检查时该病变被误诊为恶性肿瘤,尽管活检组织学检查仅显示慢性炎症。手术时,肿大淋巴结的冰冻切片显示存在巨细胞和干酪样肉芽肿,从而确诊。治疗方式为胃切除术并进行Roux-en-Y胃空肠吻合术。在该患者中,结核罕见地发生于胃十二指肠部位,且在无其他器官受累的情况下作为原发性疾病出现。

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