d'Hauthuille C, Testelin S, Taha F, Bitar G, Devauchelle B
Service de Chirurgie Maxillofaciale et Stomatologie, CHU de Nantes, Place Alexis-Ricordeau, Nantes, France.
Rev Stomatol Chir Maxillofac. 2009 Feb;110(1):3-7. doi: 10.1016/j.stomax.2008.07.007. Epub 2008 Oct 19.
The vascularized periosteal free flap transposes a non-irradiated soft tissue with neo-angiogenesis, bone induction, and osteogenesis qualities. Its technique and interest are studied for early osteoradionecrosis.
A retrospective study was made between 1992 and 2002. Thirty-four patients were selected among the 59 cases operated for osteoradionecrosis; all patients were classified stage II and I on the Epstein scale. Twenty-six patients were reconstructed using a non-periosteum free flap (bone, muscular or cutaneous flap), and eight patients were reconstructed using a "periosteum free flap". The study was clinical, radiological, and histological.
Osteoradionecrosis evolved for two of the eight patients having undergone periosteum free flap surgery. Operative morbidity and the number of reoperation were less important than for the rest of the series. The reconstruction was satisfactory on a functional and esthetic level. A bone production was noted for two patients of the "periosteum" group.
Periosteum free flap surgery is an alternative for early osteoradionecrosis. The periosteum brings osteo-induction and osteogenesis, and revascularization recorded clinically, radiologically, and histologically, even on an irradiated area.
带血管蒂游离骨膜瓣可转移具有新生血管形成、骨诱导和成骨特性的未受照射的软组织。对其技术及应用价值进行研究以用于早期放射性骨坏死。
进行一项1992年至2002年的回顾性研究。在59例因放射性骨坏死接受手术的患者中选取34例;所有患者根据爱泼斯坦量表被分类为II期和I期。26例患者采用非骨膜游离瓣(骨瓣、肌瓣或皮瓣)进行重建,8例患者采用“游离骨膜瓣”进行重建。该研究包括临床、影像学和组织学方面。
接受游离骨膜瓣手术的8例患者中有2例放射性骨坏死病情进展。手术发病率和再次手术次数比该系列其他患者少。在功能和美学层面重建效果令人满意。“骨膜”组有2例患者出现骨生成。
游离骨膜瓣手术是早期放射性骨坏死的一种治疗选择。骨膜具有骨诱导和成骨作用,并且在临床、影像学和组织学上均记录到血管再生,即使在受照射区域也是如此。