Sakurai Hiroyuki, Yamaki Takashi, Takeuchi Masaki, Soejima Kazutaka, Kono Taro, Nozaki Motohiro
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Shinjuku-ku, Tokyo 162-8666, Japan.
Microsurgery. 2009;29(2):101-6. doi: 10.1002/micr.20570.
A higher incidence of failure has been reported for free flaps transplanted to the lower extremities. However, the physiological background of this phenomenon has not been elucidated. We reviewed the 3-day postoperative hemodynamic data for 103 free flaps, including the in situ venous pressure (N = 103), arterial pressure (N = 53), and surface blood flow (N = 42). The cases were divided into two groups based on the recipient site, i.e., lower extremity (the LE group: N = 29) and the other (non-LE group: N = 74). The venous pressure was significantly higher in the LE group (26.6 +/- 2.2 vs. 14.8 +/- 1.2 mmHg), whereas the arterial pressure immediately after surgery was lower than the non-LE group. The hemodynamic data within the transferred tissues demonstrated significant differences between groups, especially in the early postoperative period. There is a possibility that the high venous pressure may aggravate the poor perfusion in tissues transferred to the lower extremities.
据报道,移植到下肢的游离皮瓣失败率较高。然而,这一现象的生理背景尚未阐明。我们回顾了103例游离皮瓣术后3天的血流动力学数据,包括原位静脉压(N = 103)、动脉压(N = 53)和表面血流量(N = 42)。根据受区部位将病例分为两组,即下肢组(LE组:N = 29)和其他组(非LE组:N = 74)。LE组的静脉压显著更高(26.6±2.2对14.8±1.2 mmHg),而术后即刻的动脉压低于非LE组。转移组织内的血流动力学数据显示两组之间存在显著差异,尤其是在术后早期。高静脉压有可能加重转移到下肢组织的灌注不良。