Harahan D, Murphy J F, O'Brien N, Gorman W, Kelehan P, Cullinane C, Deshpande D V, Clarke T, Matthews T, Gillen J
Dept of Neonatology, National Maternity Hospital, Dublin.
Ir Med J. 1991 Jun;84(2):62-3.
Non-immune hydrops fetalis is becoming a relatively more important cause of hydrops as the incidence of rhesus-related hydrops falls. We describe a series of 33 cases, occurring over a 7 year period covering most of the 1980's. We found a very wide range of aetiological factors, but cardiac conditions, both structural and dysrhythmic, formed the largest subgroup (12 cases, 36%). Seven cases (22%) remained idiopathic. Prognosis was very poor, with only 4 infants surviving. Outcome was best in the cases due to intra-uterine supraventricular tachycardia. Nineteen cases were detected antenatally, but except in the cases of fetal tachyarrhythmias, this had little effect on outcome.
随着恒河猴血型相关水肿发病率的下降，非免疫性胎儿水肿正成为相对更重要的水肿病因。我们描述了一系列33例病例，这些病例发生在涵盖20世纪80年代大部分时间的7年期间。我们发现病因范围非常广泛，但心脏疾病，包括结构性和节律性异常，构成了最大的亚组（12例，36%）。7例（22%）仍为特发性。预后非常差，只有4名婴儿存活。因宫内室上性心动过速导致的病例预后最佳。19例在产前被检测到，但除胎儿心律失常病例外，这对结局影响不大。
