Fitzpatrick Lynn R
The University of Iowa Hospitals and Clinics, Iowa City, USA.
AANA J. 2008 Oct;76(5):349-54.
This case report details the onset of masseter muscle rigidity, elevated creatine kinase levels, and rhabdomyolysis following a sevoflurane mask induction and succinylcholine administration in a 12-year-old boy. The patient had no family or personal history of neuromuscular disease or malignant hyperthermia. Hyperkalemia, metabolic acidosis, and rhabdomyolysis occurred within 75 minutes of masseter muscle rigidity. Subsequent to this event, it was recommended that the patient undergo a workup for neuromuscular disease and malignant hyperthermia with muscle biopsy. Until this workup is completed, the family should advise anesthesia providers that the patient is "malignant hyperthermia susceptible." Masseter muscle rigidity, elevated creatine kinase levels, and rhabdomyolysis will be thoroughly discussed in this article.
本病例报告详细描述了一名12岁男孩在七氟醚面罩诱导和琥珀酰胆碱给药后咬肌僵硬、肌酸激酶水平升高及横纹肌溶解症的发病情况。该患者无神经肌肉疾病或恶性高热的家族史或个人史。咬肌僵硬后75分钟内出现高钾血症、代谢性酸中毒和横纹肌溶解症。此事件发生后，建议该患者接受神经肌肉疾病和恶性高热的检查并进行肌肉活检。在检查完成之前，家属应告知麻醉医生该患者“易患恶性高热”。本文将对咬肌僵硬、肌酸激酶水平升高及横纹肌溶解症进行深入讨论。
