Labosky D A
Department of Orthopedic Surgery, West Virginia University School of Medicine, Morgantown.
Microsurgery. 1991;12(4):301-7. doi: 10.1002/micr.1920120414.
Two groups of consecutive patients treated with latissimus dorsi free myocutaneous flaps to cover lower-extremity soft-tissue defects were compared for postoperative vascular occlusion. In the first group of 13 patients (group I), there were five (38%) venous occlusions and no arterial occlusions. The second group of 15 patients (group II) was treated with selective heparinization of each venous anastomosis via a 0.35" catheter sutured into the serratus branch of the donor vein. In this group one patient suffered an arterial occlusion, but no patient suffered a venous occlusion. Statistical analysis using the Fisher exact probabilities test showed a significant decrease in vascular occlusion rate in group II, proving that selective heparinization had a beneficial effect on the venous patency rate.
对两组连续采用背阔肌游离肌皮瓣修复下肢软组织缺损的患者进行术后血管闭塞情况比较。第一组13例患者(I组),发生5例(38%)静脉闭塞,无动脉闭塞。第二组15例患者(II组),通过将一根0.35英寸的导管缝合到供体静脉的锯肌分支中,对每个静脉吻合口进行选择性肝素化处理。该组有1例患者发生动脉闭塞,但无患者发生静脉闭塞。采用Fisher精确概率检验进行统计学分析,结果显示II组血管闭塞率显著降低,证明选择性肝素化对静脉通畅率有有益影响。