Hardy Christopher J, Giaquinto Randy O, Piel Joseph E, Rohling Kenneth W, Marinelli Luca, Blezek Daniel J, Fiveland Eric W, Darrow Robert D, Foo Thomas K F
GE Global Research, Niskayuna, New York 12309, USA.
J Magn Reson Imaging. 2008 Nov;28(5):1219-25. doi: 10.1002/jmri.21463.
To determine whether the promise of high-density many-coil MRI receiver arrays for enabling highly accelerated parallel imaging can be realized in practice.
A 128-channel body receiver-coil array and custom MRI system were developed. The array comprises two clamshells containing 64 coils each, with the posterior array built to maximize signal-to-noise ratio (SNR) and the anterior array design incorporating considerations of weight and flexibility as well. Phantom imaging and human body imaging were performed using a variety of reduction factors and 2D and 3D pulse sequences.
The ratio of SNR relative to a 32-element array of similar footprint was 1.03 in the center of an elliptical loading phantom and 1.7 on average in the outer regions. Maximum g-factors dropped from 5.5 (for 32 channels) to 2.0 (for 128 channels) for 4x4 acceleration and from 25 to 3.3 for 5x5 acceleration. Residual aliasing artifacts for a right/left (R/L) reduction factor of 8 in human body imaging were significantly reduced relative to the 32-channel array.
MRI with a large number of receiver channels enables significantly higher acceleration factors for parallel imaging and improved SNR, provided losses from the coils and electronics are kept negligible.
确定高密度多线圈MRI接收阵列实现高度加速并行成像的前景在实际中是否能够实现。
开发了一个128通道的体部接收线圈阵列和定制的MRI系统。该阵列由两个蛤壳式结构组成,每个包含64个线圈,后阵列的构建旨在最大化信噪比(SNR),前阵列的设计还考虑了重量和灵活性。使用各种缩减因子以及二维和三维脉冲序列进行体模成像和人体成像。
在椭圆形加载体模中心,相对于具有相似覆盖面积的32元素阵列,SNR之比为1.03,在外围区域平均为1.7。对于4×4加速,最大g因子从5.5(32通道)降至2.0(128通道),对于5×5加速,从25降至3.3。在人体成像中,相对于32通道阵列,左右(R/L)缩减因子为8时的残余混叠伪影显著减少。
如果线圈和电子设备的损耗可忽略不计,具有大量接收通道的MRI能够实现显著更高的并行成像加速因子并提高SNR。