Malcolm W F, Hornik C, Evans A, Smith P B, Cotten C M
1Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Duke University, Durham, NC 27710, USA.
J Perinatol. 2008 Nov;28(11):782-5. doi: 10.1038/jp.2008.109.
Surgical closure of a patent ductus arteriosus (PDA) continues to be a frequent procedure among extremely preterm infants. Recent evidence indicates surgical closure is associated with worse outcomes than after medical closure. Left vocal fold paralysis is a known complication of this surgery, but there is little information available on the impact of this specific complication on long-term outcomes of these infants. In this case series, we describe the clinical course of three sets of multiple births, in which at least one infant underwent surgical closure of the PDA and subsequently developed feeding and/or breathing difficulties due to left vocal fold paralysis, and compare to their siblings who did not sustain this complication. The case series suggests that some long-term morbidities associated with surgical closure of the PDA may be attributable to this specific complication.
动脉导管未闭（PDA）的手术闭合在极早产儿中仍是一种常见的手术。最近的证据表明，与药物闭合相比，手术闭合与更差的预后相关。左侧声带麻痹是该手术已知的并发症，但关于这种特定并发症对这些婴儿长期预后的影响，几乎没有可用信息。在这个病例系列中，我们描述了三组多胞胎的临床过程，其中至少有一名婴儿接受了PDA的手术闭合，随后由于左侧声带麻痹出现喂养和/或呼吸困难，并将其与未发生这种并发症的兄弟姐妹进行比较。该病例系列表明，与PDA手术闭合相关的一些长期发病率可能归因于这种特定并发症。
