Arruda Mauricio, Armaganijan Luciana, Fahmy Tamer, Di Biase Luigi, Patel Dimpi, Natale Andrea
University Hospitals Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
J Interv Card Electrophysiol. 2009 Aug;25(2):129-33. doi: 10.1007/s10840-008-9317-z. Epub 2008 Oct 31.
Arrhythmogenic right ventricular dysplasia (ARVD) is a progressive, genetically determined fibro-fatty infiltrative myocardial disease with an estimated prevalence in the general population to be 1:5,000 to 1:10,000. ARVD leads to electrical instability that may predispose to life-threatening ventricular arrhythmia, heart failure, and sudden death. We reviewed the pathological substrate for ventricular arrhythmias, ECG findings and treatment modalities in ARVD. Importantly, novel techniques such as electroanatomic and voltage mapping has greatly improved the identification of the scared substrate in the settings of ARVD and have improved safety and efficacy of VT ablation procedures associated with this entity.
致心律失常性右室心肌病（ARVD）是一种进行性、由基因决定的纤维脂肪浸润性心肌病，在普通人群中的估计患病率为1:5000至1:10000。ARVD会导致电不稳定，可能引发危及生命的室性心律失常、心力衰竭和猝死。我们回顾了ARVD中室性心律失常的病理基础、心电图表现及治疗方式。重要的是，诸如电解剖标测和电压标测等新技术极大地提高了在ARVD情况下对瘢痕基质的识别，并提高了与此相关的室性心动过速消融手术的安全性和有效性。
