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巴比妥类药物用于治疗创伤性脑损伤后的颅内高压。

Barbiturates for the treatment of intracranial hypertension after traumatic brain injury.

作者信息

Bassin Sarice L, Bleck Thomas P

机构信息

Department of Neurology, Northwestern University Feinberg School of Medicine, N Lake Shore Drive, Chicago, Illinois 60611, USA.

出版信息

Crit Care. 2008;12(5):185. doi: 10.1186/cc7020. Epub 2008 Oct 20.

Abstract

In their article on the use of barbiturates for the treatment of intracranial hypertension after traumatic brain injury, Perez-Barcena and colleagues conclude that thiopental was more effective than pentobarbital in decreasing intracranial pressure. Here we discuss the limitations of this study and review areas of controversy surrounding barbiturate use in neurocritical care.

摘要

在他们关于使用巴比妥类药物治疗创伤性脑损伤后颅内高压的文章中,佩雷斯 - 巴尔塞纳及其同事得出结论,硫喷妥钠在降低颅内压方面比戊巴比妥更有效。在此,我们讨论这项研究的局限性,并回顾神经重症监护中巴比妥类药物使用方面存在争议的领域。

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本文引用的文献

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Serum S-100B protein monitoring in patients with severe traumatic brain injury.重型颅脑损伤患者血清S-100B蛋白监测
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