Bassin Sarice L, Bleck Thomas P
Department of Neurology, Northwestern University Feinberg School of Medicine, N Lake Shore Drive, Chicago, Illinois 60611, USA.
Crit Care. 2008;12(5):185. doi: 10.1186/cc7020. Epub 2008 Oct 20.
In their article on the use of barbiturates for the treatment of intracranial hypertension after traumatic brain injury, Perez-Barcena and colleagues conclude that thiopental was more effective than pentobarbital in decreasing intracranial pressure. Here we discuss the limitations of this study and review areas of controversy surrounding barbiturate use in neurocritical care.
在他们关于使用巴比妥类药物治疗创伤性脑损伤后颅内高压的文章中,佩雷斯 - 巴尔塞纳及其同事得出结论,硫喷妥钠在降低颅内压方面比戊巴比妥更有效。在此,我们讨论这项研究的局限性,并回顾神经重症监护中巴比妥类药物使用方面存在争议的领域。