• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Barbiturates for the treatment of intracranial hypertension after traumatic brain injury.巴比妥类药物用于治疗创伤性脑损伤后的颅内高压。
Crit Care. 2008;12(5):185. doi: 10.1186/cc7020. Epub 2008 Oct 20.
2
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 13. The use of barbiturates in the control of intracranial hypertension in severe pediatric traumatic brain injury.婴幼儿、儿童及青少年重型创伤性脑损伤的急性医疗管理指南。第13章。巴比妥类药物在控制儿童重型创伤性脑损伤颅内高压中的应用。
Pediatr Crit Care Med. 2003 Jul;4(3 Suppl):S49-52.
3
Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation.巴比妥类药物输注治疗顽固性颅内高压及其对脑氧合的影响。
Neurosurgery. 2008 Nov;63(5):880-6; discussion 886-7. doi: 10.1227/01.NEU.0000327882.10629.06.
4
High-dose barbiturates for refractory intracranial hypertension in children with severe traumatic brain injury.大剂量巴比妥类药物治疗儿童严重创伤性脑损伤伴难治性颅内高压。
Pediatr Crit Care Med. 2013 Mar;14(3):239-47. doi: 10.1097/PCC.0b013e318271c3b2.
5
Barbiturate therapy for patients with refractory intracranial hypertension following severe traumatic brain injury: its effects on tissue oxygenation, brain temperature and autoregulation.巴比妥类药物治疗重度创伤性脑损伤后难治性颅内高压患者：对组织氧合、脑温及自动调节的影响
J Clin Neurosci. 2008 Feb;15(2):143-8. doi: 10.1016/j.jocn.2006.08.014. Epub 2007 Nov 7.
6
Barbiturates for acute traumatic brain injury.用于急性创伤性脑损伤的巴比妥类药物。
Cochrane Database Syst Rev. 2000(2):CD000033. doi: 10.1002/14651858.CD000033.
7
Barbiturates for acute traumatic brain injury.用于急性创伤性脑损伤的巴比妥类药物。
Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD000033. doi: 10.1002/14651858.CD000033.pub2.
8
Indomethacin: a review of its cerebral blood flow effects and potential use for controlling intracranial pressure in traumatic brain injury patients.吲哚美辛：关于其对脑血流量的影响以及在控制创伤性脑损伤患者颅内压方面潜在用途的综述。
Neurol Res. 1999 Jul;21(5):491-9.
9
Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial.戊巴比妥与硫喷妥钠治疗创伤性脑损伤患者难治性颅内高压的随机对照试验
Crit Care. 2008;12(4):R112. doi: 10.1186/cc6999. Epub 2008 Aug 29.
10
Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study.23.4%氯化钠溶液降低创伤性脑损伤患者颅内压的效果：一项初步研究
Neurosurgery. 2005 Oct;57(4):727-36; discussion 727-36.

引用本文的文献

1
EEG is A Predictor of Neuroimaging Abnormalities in Pediatric Extracorporeal Membrane Oxygenation.脑电图是小儿体外膜肺氧合中神经影像学异常的一个预测指标。
J Clin Med. 2020 Aug 4;9(8):2512. doi: 10.3390/jcm9082512.
2
The Use of Lung Ultrasound in a Surgical Intensive Care Unit.肺部超声在外科重症监护病房的应用
Korean J Crit Care Med. 2017 Nov;32(4):323-332. doi: 10.4266/kjccm.2017.00318. Epub 2017 Nov 30.
3
Crystal structure of 5,5-bis-(4-methyl-benz-yl)pyrimidine-2,4,6(1H,3H,5H)-trione monohydrate.5,5-双-(4-甲基-苄基)嘧啶-2,4,6(1H,3H,5H)-三酮一水合物的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Jan 1;71(Pt 1):19-21. doi: 10.1107/S205698901402619X.
4
Effects of unilateral decompressive craniectomy on patients with unilateral acute post-traumatic brain swelling after severe traumatic brain injury.单侧去骨瓣减压术对重型颅脑损伤后单侧急性外伤性脑肿胀患者的影响。
Crit Care. 2009;13(6):R185. doi: 10.1186/cc8178. Epub 2009 Nov 23.

本文引用的文献

1
Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial.戊巴比妥与硫喷妥钠治疗创伤性脑损伤患者难治性颅内高压的随机对照试验
Crit Care. 2008;12(4):R112. doi: 10.1186/cc6999. Epub 2008 Aug 29.
2
Combined therapeutic hypothermia and barbiturate coma reduces interleukin-6 in the cerebrospinal fluid after aneurysmal subarachnoid hemorrhage.联合治疗性低温与巴比妥类药物昏迷可降低动脉瘤性蛛网膜下腔出血后脑脊液中的白细胞介素-6水平。
J Neurosurg Anesthesiol. 2008 Jul;20(3):193-8. doi: 10.1097/ANA.0b013e31817996bf.
3
Barbiturate therapy for patients with refractory intracranial hypertension following severe traumatic brain injury: its effects on tissue oxygenation, brain temperature and autoregulation.巴比妥类药物治疗重度创伤性脑损伤后难治性颅内高压患者：对组织氧合、脑温及自动调节的影响
J Clin Neurosci. 2008 Feb;15(2):143-8. doi: 10.1016/j.jocn.2006.08.014. Epub 2007 Nov 7.
4
Serum S-100B protein monitoring in patients with severe traumatic brain injury.重型颅脑损伤患者血清S-100B蛋白监测
Intensive Care Med. 2007 Feb;33(2):255-60. doi: 10.1007/s00134-006-0463-4. Epub 2006 Dec 2.
5
Neuroprotection in transient focal cerebral ischemia by combination drug therapy and mild hypothermia: comparison with customary therapeutic regimen.联合药物治疗与轻度低温对短暂性局灶性脑缺血的神经保护作用：与传统治疗方案的比较
Stroke. 2003 Jun;34(6):1526-32. doi: 10.1161/01.STR.0000070841.31224.29. Epub 2003 May 1.
6
Hypothermia and thiopentone sodium: individual and combined neuroprotective effects on cortical cultures exposed to prolonged hypoxic episodes.体温过低与硫喷妥钠：对经历长时间缺氧发作的皮层培养物的个体及联合神经保护作用
J Neurosci Res. 2002 May 1;68(3):352-62. doi: 10.1002/jnr.10237.
7
Barbiturates for acute traumatic brain injury.用于急性创伤性脑损伤的巴比妥类药物。
Cochrane Database Syst Rev. 2000(2):CD000033. doi: 10.1002/14651858.CD000033.
8
Electroencephalographic burst suppression is not required to elicit maximal neuroprotection from pentobarbital in a rat model of focal cerebral ischemia.在局灶性脑缺血大鼠模型中，引发戊巴比妥的最大神经保护作用并不需要脑电图爆发抑制。
Anesthesiology. 1996 Jun;84(6):1475-84. doi: 10.1097/00000542-199606000-00024.
9
Dose of thiopental, pentobarbital, and phenytoin for maximal therapeutic effects in cerebral ischemic anoxia.硫喷妥钠、戊巴比妥和苯妥英在脑缺血缺氧中产生最大治疗效果的剂量。
Crit Care Med. 1983 Jun;11(6):452-9. doi: 10.1097/00003246-198306000-00013.
10
High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury.大剂量巴比妥类药物对重型颅脑损伤患者颅内压升高的控制作用
J Neurosurg. 1988 Jul;69(1):15-23. doi: 10.3171/jns.1988.69.1.0015.

巴比妥类药物用于治疗创伤性脑损伤后的颅内高压。

Barbiturates for the treatment of intracranial hypertension after traumatic brain injury.

作者信息

Bassin Sarice L, Bleck Thomas P

机构信息

Department of Neurology, Northwestern University Feinberg School of Medicine, N Lake Shore Drive, Chicago, Illinois 60611, USA.

出版信息

Crit Care. 2008;12(5):185. doi: 10.1186/cc7020. Epub 2008 Oct 20.

DOI:10.1186/cc7020
PMID:18983702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2592754/
Abstract

In their article on the use of barbiturates for the treatment of intracranial hypertension after traumatic brain injury, Perez-Barcena and colleagues conclude that thiopental was more effective than pentobarbital in decreasing intracranial pressure. Here we discuss the limitations of this study and review areas of controversy surrounding barbiturate use in neurocritical care.

摘要

在他们关于使用巴比妥类药物治疗创伤性脑损伤后颅内高压的文章中，佩雷斯 - 巴尔塞纳及其同事得出结论，硫喷妥钠在降低颅内压方面比戊巴比妥更有效。在此，我们讨论这项研究的局限性，并回顾神经重症监护中巴比妥类药物使用方面存在争议的领域。