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乳突腔填塞中羟基磷灰石骨水泥的并发症。

Complications with hydroxyapatite cement in mastoid cavity obliteration.

作者信息

Ridenour Janell S, Poe Dennis S, Roberson David W

机构信息

Department of Otolaryngology, Children's Hospital, Boston, MA, USA.

出版信息

Otolaryngol Head Neck Surg. 2008 Nov;139(5):641-5. doi: 10.1016/j.otohns.2008.07.020.

Abstract

OBJECTIVE

To determine whether hydroxyapatite (HA) bone cement is a suitable material for mastoid cavity obliteration.

STUDY DESIGN & SETTING: Retrospective case review; tertiary care pediatric hospital.

PATIENTS

Three patients, aged 11 to 16 years, underwent canal wall down mastoidectomy for removal of cholesteatomas.

INTERVENTION

Mastoid cavity obliteration was performed with hydroxyapatite bone cement.

MAIN OUTCOME MEASURES

Failure was defined as the necessity for HA explantation.

RESULTS

All three patients required revision surgery to remove the HA cement. Two patients (one primary and one second look with obliteration) presented with granulations in the mastoid cavity, surrounding the cement. The third patient's intraoperative findings included extensive skull base osteitis with erosion of the posterior and middle fossa dural plates, and fistulae of the lateral and superior semicircular canals. All patients recovered fully after removal of the HA cement.

CONCLUSION

This study raises concerns over the use of HA cement for mastoid cavity obliteration. Three of three implanted patients required revision surgery, two with delayed failure of integration and infection, and one with severe osteitis and significant complications.

摘要

目的

确定羟基磷灰石(HA)骨水泥是否是用于乳突腔填塞的合适材料。

研究设计与地点

回顾性病例分析;三级护理儿童医院。

患者

3例年龄在11至16岁之间的患者接受了开放式乳突根治术以切除胆脂瘤。

干预措施

用羟基磷灰石骨水泥进行乳突腔填塞。

主要观察指标

失败定义为需要取出HA骨水泥。

结果

所有3例患者均需要再次手术取出HA骨水泥。2例患者(1例初次手术和1例二次探查并填塞)在乳突腔内、骨水泥周围出现肉芽组织。第3例患者术中发现广泛的颅底骨炎,伴有后颅窝和中颅窝硬脑膜板侵蚀,以及外半规管和上半规管瘘管。取出HA骨水泥后,所有患者均完全康复。

结论

本研究对使用HA骨水泥进行乳突腔填塞提出了担忧。3例植入患者中有3例需要再次手术,2例出现整合延迟失败和感染,1例出现严重骨炎和明显并发症。

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