米曲霉固态培养与深层培养中未折叠蛋白反应的比较。
A comparison of the unfolded protein response in solid-state with submerged cultures of Aspergillus oryzae.
作者信息
Ye Lei, Pan Li
机构信息
College of Bioscience and Bioengineering, South China University of Technology, Guangzhou, China.
出版信息
Biosci Biotechnol Biochem. 2008 Nov;72(11):2998-3001. doi: 10.1271/bbb.80146. Epub 2008 Nov 7.
The unfolded protein response (UPR) is a regulatory system to maintain the homeostasis of ER functions. Here we report a comparison of express levels of UPR relevant genes in Aspergillus oryzae between solid-state and submerged cultivation. The results were that up-regulation of the UPR mechanism in solid-state culture was higher than in submerged culture (heat-shock or non-stress conditions). This might have been a result of changing culture conditions.
未折叠蛋白反应（UPR）是一种维持内质网功能稳态的调节系统。在此，我们报告了米曲霉在固态培养和液体深层培养条件下与UPR相关基因表达水平的比较。结果显示，在固态培养中UPR机制的上调高于液体深层培养（热休克或非应激条件下）。这可能是培养条件变化的结果。
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