Li Xiang, Wang Chengtao
Department of Mechanical Engineering, Shanghai Jiaotong University, Shanghai 200240, China.
Sheng Wu Gong Cheng Xue Bao. 2008 Aug;24(8):1321-6.
As one of the key factors for tissue engineering, scaffolds affect the spread and proliferation of seeded cells and the formation of new tissue. Although conventional methods can produce porous scaffolds with different porosities, they are lack controls the porous structures of the scaffolds. In recent years, rapid prototyping (RP) techniques have been developed and have successfully applied to fabricate TE scaffolds. RP techniques can provide accurate control over internal pore architectures and complex-shapes. As a result of these techniques, ideal tissue-engineered constructs could be prepared. This paper reviewed the advantages, potential and future directions of RP techniques in the design and fabrication of TE scaffolds.
作为组织工程的关键因素之一，支架会影响接种细胞的扩散和增殖以及新组织的形成。尽管传统方法可以制造具有不同孔隙率的多孔支架，但它们缺乏对支架多孔结构的控制。近年来，快速成型（RP）技术得到了发展，并已成功应用于制造组织工程支架。RP技术可以对内部孔隙结构和复杂形状提供精确控制。由于这些技术，可以制备理想的组织工程构建体。本文综述了RP技术在组织工程支架设计和制造中的优势、潜力及未来发展方向。
