关于Spo16与并发系数
On Spo16 and the coefficient of coincidence.
作者信息
Stahl Franklin W, Foss Henriette M
机构信息
Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403-1229, USA.
出版信息
Genetics. 2009 Jan;181(1):327-30. doi: 10.1534/genetics.108.097071. Epub 2008 Nov 10.
spo16 mutants in yeast were reported to have reduced map lengths, a high frequency of nondisjunction in the first meiotic division, and essentially unchanged coefficients of coincidence. Were all crossing over in yeast subject to interference, such data would suggest that the "designation" of recombination events to become crossovers is separable from the "implementation" of that crossing over. In the presence of coexisting interference and noninterference phases of crossing over, however, lack of change in the coefficient of coincidence may show only that spo16 reduces crossing over in the two phases by a similar factor.
据报道，酵母中的spo16突变体具有缩短的图谱长度、第一次减数分裂中非分离的高频率，以及基本不变的并发系数。如果酵母中的所有交换都受到干涉，那么这些数据将表明，重组事件成为交换的“指定”与该交换的“实施”是可分离的。然而，在存在交换的干涉和非干涉共存阶段的情况下，并发系数缺乏变化可能仅表明spo16在这两个阶段中以相似的因子减少了交换。
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