Kajihara Noriyoshi, Asou Toshihide, Takeda Yuko, Kosaka Yoshimichi, Miyata Daiki, Nagafuchi Hiroyuki, Yasui Seiyo
Department of Cardiovascular Surgery, Kanagawa Children's Medical Center, Yokohama, Kanagawa, Japan.
Interact Cardiovasc Thorac Surg. 2009 Feb;8(2):211-5. doi: 10.1510/icvts.2008.187963. Epub 2008 Nov 11.
Functionally single ventricle (f-SV) is susceptible to volume overload. Atrioventricular valve regurgitation (AVVR) tends to develop and ventricular function deteriorates due to excessive pulmonary blood flow following modified Blalock-Taussig shunt (mBTS). On the other hand, a small caliber graft has risks of early obstruction and poor growth of pulmonary vascular beds. We assessed the effect of mBTS with a 3-mm graft to circumvent volume overload in f-SV on achievement of the right heart bypass. Eleven neonates and infants with f-SV at the median age of 24 days underwent mBTS using a 3-mm graft between August 2004 and June 2007. There were no early deaths, but there was one late death. All survivors achieved bidirectional cavopulmonary shunt (BCPS) at 4.2 months after mBTS. Cardiac catheterization demonstrated sufficient growth of the pulmonary artery (pulmonary artery index, 268+/-98 cm(2)/m(2)), low pulmonary vascular resistance (1.4+/-0.9 U.m(2)). The AVVR remained mild or less. Ventricular end-diastolic volume and ejection fraction were 171+/-61% of the normal value and 64+/-6%, respectively. We conclude that a 3-mm mBTS was useful in preventing f-SV from volume overload and was effective for growing good pulmonary vasculature and achieving a right heart bypass.
功能性单心室(f-SV)易发生容量超负荷。由于改良布莱洛克-陶西格分流术(mBTS)后肺血流量过多,房室瓣反流(AVVR)容易出现,心室功能也会恶化。另一方面,小口径移植物存在早期梗阻以及肺血管床发育不良的风险。我们评估了采用3毫米移植物的mBTS对避免f-SV容量超负荷及实现右心旁路的效果。2004年8月至2007年6月期间,11例中位年龄为24天的f-SV新生儿和婴儿接受了使用3毫米移植物的mBTS。无早期死亡病例,但有1例晚期死亡。所有幸存者在mBTS后4.2个月实现了双向腔肺分流(BCPS)。心导管检查显示肺动脉充分发育(肺动脉指数,268±98 cm²/m²),肺血管阻力较低(1.4±0.9 U·m²)。AVVR仍为轻度或更低。心室舒张末期容积和射血分数分别为正常值的171±61%和64±6%。我们得出结论,3毫米的mBTS有助于防止f-SV容量超负荷,对促进良好的肺血管发育及实现右心旁路有效。