基于三（2-吡啶甲基）胺配体的铁（III）单核异羟肟酸酯和羟肟酸酯配合物的合成与表征

Synthesis and characterization of mononuclear hydroxamato and hydroximato complexes of iron(III) based on the tris-(2-pyridylmethyl)amine ligand.

作者信息

Galardon Erwan, Selkti Mohamed, Roussel Pascal, Tomas Alain, Artaud Isabelle

机构信息

Laboratoire de Chimie et Biochimie Toxicologiques et Pharmacologiques, UMR 8601 CNRS, Université Paris Descartes, 45 rue des St-Pères, 75270 Paris Cedex 06, France.

出版信息

Dalton Trans. 2008 Dec 7(45):6415-20. doi: 10.1039/b808967a. Epub 2008 Oct 6.

DOI:10.1039/b808967a

PMID:19002328

Abstract

The reaction of acetohydroxamic (CH3C(O)-NHOH), benzhydroxamic acid (PhC(O)-NHOH) or 1-hydroxypyridin-2(1H)-one (pyrC(O)-NOH) in the presence of tris-(2-pyridylmethyl)amine (TPA), sodium methoxide and an iron(III) salt yields the mononuclear complexes [Fe(TPA)(CH3C(O)-NHO)]2+ (), [Fe(TPA)(PhC(O)-NHO)]2+ () and [Fe(TPA)(pyrC(O)-NO)]2+ (). The hydroxamato complexes and are easily converted to their hydroximato form [Fe(TPA)(CH3C(O)=NO)]+ () and [Fe(TPA)(PhC(O)=NO)]+ () by addition of base. The complexes described were characterized by UV-vis spectroscopy, EPR and cyclic voltammetry, as well as single-crystal X-ray crystallography for and .

摘要

在三（2 - 吡啶甲基）胺（TPA）、甲醇钠和铁（III）盐存在的情况下，乙酰氧肟酸（CH₃C(O)-NHOH）、苯甲羟肟酸（PhC(O)-NHOH）或1 - 羟基吡啶 - 2(1H)-酮（pyrC(O)-NOH）反应生成单核配合物[Fe(TPA)(CH₃C(O)-NHO)]²⁺（）、[Fe(TPA)(PhC(O)-NHO)]²⁺（）和[Fe(TPA)(pyrC(O)-NO)]²⁺（）。通过加入碱，异羟肟酸配合物和很容易转化为它们的羟胺形式[Fe(TPA)(CH₃C(O)=NO)]⁺（）和[Fe(TPA)(PhC(O)=NO)]⁺（）。所描述的配合物通过紫外可见光谱、电子顺磁共振和循环伏安法进行了表征，以及对和进行了单晶X射线晶体学分析。