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未行血管造影栓塞术的青少年鼻咽血管纤维瘤的外科治疗

Surgical management of juvenile nasopharyngeal angiofibroma without angiographic embolization.

作者信息

Ahmad Raja, Ishlah Wan, Azilah Norie, Rahman Jamalludin A

机构信息

Department of Otolaryngology-Head and Neck Surgery, International Islamic University Malaysia, Pahang Darul Makmur, Malaysia.

出版信息

Asian J Surg. 2008 Oct;31(4):174-8. doi: 10.1016/S1015-9584(08)60081-0.

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males. Surgery remains the primary treatment of choice. JNA has always presented a management challenge to surgeons because of its vascular nature, site of occurrence, and local tissue destruction. The surgical approaches are either standard open method which include external or intraoral incisions, or the recent advanced approach, i.e. via using the endonasal endoscope. It is widely accepted that the use of preoperative angiographic embolization reduces the occurrence of intraoperative bleeding and facilitates tumour removal. However, angiographic embolization is not available at all centres. The purpose of this article is to present our experience with five patients diagnosed with JNA who were resected without embolization, using various surgical approaches. Two tumours were removed via endonasal endoscopic surgery. None of the tumours were embolized prior to surgery. We highlight the preoperative evaluation of tumour extent, using both computed tomography (CT) and magnetic resonance angiography, and the importance of temporary clamping of the external carotid artery intraoperatively. Our results suggest that the latter procedure is a safe and effective means of facilitating surgery and reducing intraoperative bleeding.

摘要

青少年鼻咽血管纤维瘤(JNA)是一种罕见的良性肿瘤,几乎仅发生于青春期男性的鼻咽部。手术仍然是主要的治疗选择。由于其血管性质、发生部位及局部组织破坏,JNA一直给外科医生带来治疗挑战。手术入路要么是标准的开放方法,包括外部或口内切口,要么是最近的先进方法,即通过鼻内镜。术前血管造影栓塞术的应用可减少术中出血并便于肿瘤切除,这一点已被广泛接受。然而,并非所有中心都能进行血管造影栓塞术。本文的目的是介绍我们对5例诊断为JNA且未进行栓塞而采用各种手术方法切除的患者的经验。2例肿瘤通过鼻内镜手术切除。所有肿瘤在手术前均未进行栓塞。我们强调了使用计算机断层扫描(CT)和磁共振血管造影对肿瘤范围进行术前评估,以及术中临时夹闭颈外动脉的重要性。我们的结果表明,后一种方法是促进手术和减少术中出血的一种安全有效的手段。

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