Cerwinka Wolfgang H, Grattan-Smith J Damien, Scherz Hal C, Kirsch Andrew J
Pediatric Urology at Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA 30342, USA.
J Pediatr Urol. 2009 Apr;5(2):114-8. doi: 10.1016/j.jpurol.2008.10.005. Epub 2008 Nov 18.
With the increasing popularity of endoscopic treatment for vesicoureteral reflux (VUR) in children, dextranomer/hyaluronic acid copolymer (Deflux) implants are more frequently detected by magnetic resonance imaging (MRI). Such findings on MRI may be misinterpreted and lead to unnecessary intervention. The objective of this study was to characterize the appearance of Deflux implants on MRI.
Between July 2001 and November 2007, hospital charts of patients with a history of Deflux injection for VUR were evaluated to identify those who had subsequent MRI studies. The indications were determined, and the appearance of Deflux implants analyzed and compared to findings on ultrasound, voiding cystourethrography and kidney ureter bladder radiography.
Of 893 patients who underwent endoscopic treatment for VUR, subsequently 16 patients (1.8%) had MRI scans. Twenty-seven Deflux implants were identified on MRI as bright structures on T2-weighted sequences only. Neither T1-weighted images nor excretory MR urography visualized the Deflux implants, which did not enhance with gadolinium. Deflux was not detected by kidney ureter bladder radiography; however, voiding cystourethrography and more reliably ultrasound could identify implants.
Deflux implants appear on MRI as bright structures on T2-weighted sequences. History of VUR/VUR treatment and the presence of a single urinary system should provide reassurance and prevent inappropriate intervention for misdiagnosed ureteroceles.
随着儿童膀胱输尿管反流(VUR)内镜治疗的日益普及,磁共振成像(MRI)更频繁地检测到葡聚糖omer/透明质酸共聚物(Deflux)植入物。MRI上的此类发现可能会被误解并导致不必要的干预。本研究的目的是描述Deflux植入物在MRI上的表现。
在2001年7月至2007年11月期间,对有Deflux注射治疗VUR病史的患者的医院病历进行评估,以确定那些随后进行了MRI检查的患者。确定适应症,并分析Deflux植入物的表现,并与超声、排尿性膀胱尿道造影和肾输尿管膀胱造影的结果进行比较。
在893例接受VUR内镜治疗的患者中,随后有16例(1.8%)进行了MRI扫描。MRI上仅在T2加权序列上将27个Deflux植入物识别为明亮结构。T1加权图像和排泄性磁共振尿路造影均未显示Deflux植入物,其在钆增强时也不强化。肾输尿管膀胱造影未检测到Deflux;然而,排尿性膀胱尿道造影以及更可靠的超声可以识别植入物。
Deflux植入物在MRI上表现为T2加权序列上的明亮结构。VUR/VUR治疗史和单一泌尿系统的存在应能让人放心,并防止对误诊的输尿管囊肿进行不适当的干预。