Isojima Tsuyoshi, Yokoya Susumu, Ito Junko, Horikawa Reiko, Tanaka Toshiaki
Clinical Research Center, National Center for Child Health and Development, Ohkura, Setagaya-ku, Tokyo, Japan.
Acta Paediatr. 2009 Mar;98(3):513-8. doi: 10.1111/j.1651-2227.2008.01132.x. Epub 2008 Nov 17.
To evaluate the prevalence of overweight in girls with Turner syndrome (TS) as classified by the two major anthropometric indices, body mass index (BMI) and weight-for-height (WFH) and to make growth reference charts of them for comparison with those of the normal population.
The samples for analysis were obtained from a retrospective cohort. In total, 1447 girls' cross-sectional data were analysed. Subjects were divided into four groups by ages: group A (0-5.99 years), B (6-10.99 years), C (11-15.99 years) and D (16-20.99 years). The cut-off values of overweight by BMI and WFH were those of the 90th percentile and 120 percent, respectively and the prevalence was calculated. For constructing growth reference charts, the LMS method was used.
The prevalence of overweight differed between the two indices. The proportions of the coincidental classification in all subjects, group A, B, C and D were 82.53%, 89.96%, 91.79%, 69.98% and 60.61%, respectively. These differences corresponded to the difference of age-dependent patterns of the two indices from those of the normal population, as judged from the growth charts constructed with all subjects.
A discrepancy in the prevalence of overweight as classified by BMI and WFH for girls with TS was detected.
通过两种主要人体测量指标,即体重指数(BMI)和身高体重比(WFH),评估特纳综合征(TS)女孩超重的患病率,并制作她们的生长参考图表,以便与正常人群的图表进行比较。
分析样本来自回顾性队列。总共分析了1447名女孩的横断面数据。受试者按年龄分为四组:A组(0 - 5.99岁)、B组(6 - 10.99岁)、C组(11 - 15.99岁)和D组(16 - 20.99岁)。BMI和WFH超重的临界值分别为第90百分位数和第120百分位数,并计算患病率。为构建生长参考图表,使用了LMS方法。
两种指标超重的患病率不同。所有受试者、A组、B组、C组和D组中一致分类的比例分别为82.53%、89.96%、91.79%、69.98%和60.61%。从所有受试者构建的生长图表判断,这些差异对应于这两种指标与正常人群年龄相关模式的差异。
检测到TS女孩中按BMI和WFH分类的超重患病率存在差异。