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日本饮食与19年死亡率:1980年全国非传染性疾病及其在老年人中的趋势前瞻性观察综合项目

A Japanese diet and 19-year mortality: national integrated project for prospective observation of non-communicable diseases and its trends in the aged, 1980.

作者信息

Nakamura Yasuyuki, Ueshima Hirotsugu, Okamura Tomonori, Kadowaki Takashi, Hayakawa Takehito, Kita Yoshikuni, Abbott Robert D, Okayama Akira

机构信息

Cardiovascular Epidemiology, Kyoto Women's University, 35 Imakumano Kitahiyoshi-cho, Higashiyama-ku, Kyoto 605-8501, Japan.

出版信息

Br J Nutr. 2009 Jun;101(11):1696-705. doi: 10.1017/S0007114508111503. Epub 2008 Nov 20.

Abstract

Few studies have examined the association between Japanese diet and mortality outcomes. We analysed the relationship between a healthy Japanese diet and all-cause and cause-specific mortality using the database from the National Integrated Project for Prospective Observation of Non-Communicable Diseases and its Trends in the Aged, 1980. At baseline in 1980, data were collected on study participants aged > or =30 years from randomly selected areas in Japan. We defined a measure of a healthy reduced-salt Japanese diet based on seven components from FFQ. The total score ranged from 0 to 7, with 0 being least healthy and 7 being most healthy. Participants were divided into approximate tertiles of dietary scores (0-2, 3 and 4-7 scores). After excluding participants with co-morbidities, we followed 9086 participants (44 % men) for 19 years. There were 1823 all-cause and 654 cardiovascular deaths during the follow-up. With the dietary score group 0-2 serving as a reference, the Cox multivariate-adjusted hazard ratios for groups with scores 3 and 4-7 were 0.92 (95 % CI 0.83, 1.04) and 0.78 (95 % CI 0.70, 0.88) for all-cause mortality (trend P < 0.0001), and 0.91 (95 % CI 0.75, 1.10) and 0.80 (95 % CI 0.66, 0.97) for cardiovascular mortality (trend P = 0.022). Adherence to a healthy reduced-salt Japanese diet was associated with an approximate 20 % lower rate of all-cause and cardiovascular mortality.

摘要

很少有研究探讨日本饮食与死亡率之间的关联。我们利用1980年全国非传染性疾病及其在老年人中的趋势前瞻性观察综合项目数据库,分析了健康的日本饮食与全因死亡率和特定病因死亡率之间的关系。1980年基线时,从日本随机选取的地区收集了年龄≥30岁的研究参与者的数据。我们基于食物频率问卷的七个组成部分定义了一种健康的低盐日本饮食指标。总分范围为0至7分,0分表示最不健康,7分表示最健康。参与者被分为饮食得分的近似三分位数(0 - 2分、3分和4 - 7分)。在排除患有合并症的参与者后,我们对9086名参与者(44%为男性)进行了19年的随访。随访期间有1823例全因死亡和654例心血管死亡。以饮食得分0 - 2分组为参照,得分3分和4 - 7分组的Cox多变量调整风险比,全因死亡率分别为0.92(95%置信区间0.83, 1.04)和0.78(95%置信区间0.70, 0.88)(趋势P < 0.0001),心血管死亡率分别为0.91(95%置信区间0.75, 1.10)和0.80(95%置信区间0.66, 0.97)(趋势P = 0.022)。坚持健康的低盐日本饮食与全因死亡率和心血管死亡率降低约20%相关。

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