经皮冠状动脉介入治疗中血栓抽吸用于心原性休克。

Thrombus aspiration during primary angioplasty for cardiogenic shock.

出版信息

Int J Cardiol. 2010 Apr 1;140(1):111-3. doi: 10.1016/j.ijcard.2008.10.038. Epub 2008 Nov 25.

DOI:10.1016/j.ijcard.2008.10.038

PMID:19033082

Abstract

We sought to assess the clinical efficacy of thrombus aspiration during primary percutaneous coronary interventions (PCI) in patients presenting with ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). We retrospectively selected 44 patients with CS out of a population of 842 STEMI patients treated with primary PCI at our Hospital between March 2003 and October 2007. Twenty-six patients died during hospital stay (59.1%, Group 1), whereas the remaining 18 were discharged (40.9%, Group 2). Post-procedural ST-segment resolution was greater (68.0%+/-35.6 vs. 43.0%+/-35.0; p=0.06) and in-hospital mortality was significantly lower (21.4% vs 76.6%; p<0.01) in patients treated by TA as compared to patients undergoing standard PCI. At multivariate logistic regression analysis, TA was the only variable independently associated with survival.

摘要

我们旨在评估在因 ST 段抬高型心肌梗死（STEMI）并发心原性休克（CS）而接受直接经皮冠状动脉介入治疗（PCI）的患者中血栓抽吸的临床疗效。我们回顾性地选择了 2003 年 3 月至 2007 年 10 月期间在我院接受直接 PCI 治疗的 842 例 STEMI 患者中的 44 例 CS 患者。26 例患者在住院期间死亡（59.1%，第 1 组），而其余 18 例出院（40.9%，第 2 组）。与接受标准 PCI 的患者相比，接受 TA 治疗的患者术后 ST 段回落更大（68.0%+/-35.6 比 43.0%+/-35.0；p=0.06），住院死亡率显著降低（21.4%比 76.6%；p<0.01）。多变量逻辑回归分析显示，TA 是唯一与生存相关的独立变量。