[意外的局灶性肠道 18-FDG 摄取部位：是否应进行系统研究？]

[Unexpected focal bowel 18-FDG uptake sites: should they be systematically investigated?].

作者信息

Tessonnier Laetitia, Gonfrier Sebastien, Carrier Patricia, Valerio Laure, Mouroux Jérôme, Benisvy Danielle, Viau Philippe, Girma Astrid, Bussière Françoise, Darcourt Jacques

机构信息

Service de médecine nucléaire, fédération de médecine nucléaire CAL, centre Antoine-Lacassagne, CHU de Nice, 33, avenue de Valombrose, 06189 Nice cedex, France.

出版信息

Bull Cancer. 2008 Nov;95(11):1083-7. doi: 10.1684/bdc.2008.0740.

DOI:10.1684/bdc.2008.0740

PMID:19036681

Abstract

The purpose of the present study was to retrospectively evaluate the nature and significance of unexpected focal 18-FDG uptake localized by PET/CT within the intestinal tract. Methods. The data of 4,033 PET/CT were retrospectively reviewed. One hundred and eighty PET/CT showed unexpected focal uptakes (patients with known intestinal neoplasia were excluded). Among them, 42 patients corresponding to 47 focal uptake sites were investigated by endoscopy or surgery. Results. Height endoscopy results were negative (17%). We found 25 adenomatous polyps (53.2%), 10 neoplasms (21.3%) and 4 inflammatory lesions (8.5%). 18-FDG uptake values were not statistically different between the 4 groups. Conclusion. Eighty-three percent of unexpected intestinal foci of hypermetabolism are either inflammatory, malignant or premalignant lesions. These results justify systematic investigation of these lesions.

摘要

本研究的目的是回顾性评估PET/CT在肠道内发现的意外局灶性18-FDG摄取的性质和意义。方法。回顾性分析4033例PET/CT数据。180例PET/CT显示意外局灶性摄取（排除已知肠道肿瘤患者）。其中，42例患者共47个局灶性摄取部位接受了内镜检查或手术。结果。高度内镜检查结果为阴性（17%）。我们发现25例腺瘤性息肉（53.2%）、10例肿瘤（21.3%）和4例炎性病变（8.5%）。4组之间的18-FDG摄取值无统计学差异。结论。83%的意外肠道高代谢灶为炎性、恶性或癌前病变。这些结果证明对这些病变进行系统检查是合理的。