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急性心肌梗死患者的常规冠状动脉造影随访及后续血运重建

Routine coronary angiographic follow-up and subsequent revascularization in patients with acute myocardial infarction.

作者信息

Shimada Katsunori, Kasanuki Hiroshi, Hagiwara Nobuhisa, Ogawa Hiroshi, Yamaguchi Naohito

机构信息

Department of Hygiene and Public Health II, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.

出版信息

Heart Vessels. 2008 Nov;23(6):383-9. doi: 10.1007/s00380-008-1060-y. Epub 2008 Nov 27.

Abstract

The aims of the present study are to: (1) clarify the angiographic follow-up (AFU) rate after discharge; (2) elucidate the characteristics of those undergoing it; and (3) determine the impact of AFU on subsequent revascularization procedures among patients with acute myocardial infarction (AMI). Three thousand and twenty-one consecutive patients presenting within 48 h of AMI onset were enrolled from 17 centers in Japan between January 1999 and June 2001. To clarify the frequency of AFU and their characteristics, 2736 patients who survived at discharge were analyzed. Among 1160 patients matched by propensity score, the impact of AFU on subsequent revascularization was analyzed. Of 2736 patients, 1367 (50%) underwent AFU and constituted the lower-risk population. Of the 580 matched patient pairs, 120 (21%) in the clinical follow-up group and 198 (34%) in the AFU group underwent subsequent revascularization (hazard ratio 7.54; 95% confidence interval 5.74-9.91). Of the 198 patients in the AFU group, 157 (79%) underwent revascularization at the discretion of the responsible physician based on angiographic findings. Angiographic follow-up led to more subsequent revascularization. More evidence would be necessary to determine the effectiveness and the methods by which patients are selected.

摘要

本研究的目的是

(1)明确出院后的血管造影随访(AFU)率;(2)阐明接受AFU患者的特征;(3)确定AFU对急性心肌梗死(AMI)患者后续血运重建手术的影响。1999年1月至2001年6月期间,从日本17个中心连续纳入了3021例在AMI发病后48小时内就诊的患者。为了明确AFU的频率及其特征,对2736例出院时存活的患者进行了分析。在1160例倾向评分匹配的患者中,分析了AFU对后续血运重建的影响。在2736例患者中,1367例(50%)接受了AFU,构成低风险人群。在580对匹配的患者中,临床随访组有120例(21%),AFU组有198例(34%)接受了后续血运重建(风险比7.54;95%置信区间5.74-9.91)。在AFU组的198例患者中,157例(79%)根据血管造影结果由负责医生酌情进行了血运重建。血管造影随访导致更多的后续血运重建。需要更多证据来确定其有效性以及患者的选择方法。

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