Che Lin, Wang Le-min, Jiang Jin-fa, Xu Wen-jun, Zhang Qi-ping
Department of Cardiology, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China.
Zhonghua Yi Xue Za Zhi. 2008 Jul 8;88(26):1820-3.
To investigate the safety and effects of early submaximal cardiopulmonary exercise test (CPET) and cardiac rehabilitation for patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI).
94 patients with AMI after PCI were randomly divided into 2 groups: exercise group undergoing anaerobic rehabilitation training based on anaerobic threshold (AT) exercise prescription for 3 months, and control group, conducting exercise according to the needs of the patients themselves. Three months later, the exercise cardiopulmonary function was evaluated.
In the first CPET 89 patients attained their anaerobic threshold (AT) and their heart rates were lower than their target heart rates following the exercise test. The oxygen consumption at the anaerobic threshold (VO2AT) 3 months later of the exercise group was [(12.6 +/- 2.9) ml x min(-1) x kg(1)], significantly greater and that before the exercise [(10.5 x 2.9) ml x min x kg(-1), P = 0.000]. The peak oxygen uptake (VO2 pea) 3 months of the exercise group was (20 +/- 4) ml x min(-1) x kg(-1), signficantly greater then that before exercise [(14 +/- 4) ml x min(-1) x kg(-1), P = 0.000]. The LAT 3 months of the exercise group was (42 +/- 16) J x s(-1), significantly higher than that before exercise p [(33 +/- 20) J x s(-1), P = 0.000]. The workload at peak level (Lpeak) 3 months of the exercise group was (89 +/- 14) J x s(-1) significantly greater than thatbefore exercise [(66 +/- 21) J x s(-1), P = 0.000]. And the VO2pea and Lpeak of 3 months later of the control group were [(19 +/- 4) ml x min(-l) x kg(-1)) and (80 +/- 14) J x s(-1)] respectively, both significantly higher than those before exercise [(14 +/- 4) ml x min(-1) x kg(-1) and (64 +/- 21) J x s(-1), both P = 0.000].
The early submaximal CPET and cardiac rehabilitation for patients with AMI after PCI are not only safe but also can improve their exercise capacity.
探讨早期次极量心肺运动试验（CPET）及心脏康复对急性心肌梗死（AMI）患者经皮冠状动脉介入治疗（PCI）后的安全性及效果。
将94例PCI术后的AMI患者随机分为两组：运动组根据无氧阈（AT）运动处方进行3个月的无氧康复训练，对照组根据患者自身需求进行运动。3个月后，评估运动心肺功能。
在首次CPET中，89例患者达到无氧阈（AT），且运动试验后的心率低于目标心率。运动组3个月后的无氧阈耗氧量（VO2AT）为[（12.6±2.9）ml·min⁻¹·kg⁻¹]，显著高于运动前[（10.5±2.9）ml·min⁻¹·kg⁻¹，P = 0.000]。运动组3个月后的峰值摄氧量（VO2peak）为（20±4）ml·min⁻¹·kg⁻¹，显著高于运动前[（14±4）ml·min⁻¹·kg⁻¹，P = 0.000]。运动组3个月后的无氧阈功率（LAT）为（42±16）J·s⁻¹，显著高于运动前[（33±20）J·s⁻¹，P = 0.000]。运动组3个月后的峰值运动负荷（Lpeak）为（89±14）J·s⁻¹，显著高于运动前[（66±21）J·s⁻¹，P = 0.000]。对照组3个月后的VO2peak和Lpeak分别为[（19±4）ml·min⁻¹·kg⁻¹]和（80±14）J·s⁻¹，均显著高于运动前[（14±4）ml·min⁻¹·kg⁻¹和（64±21）J·s⁻¹，P均 = 0.000]。
早期次极量CPET及心脏康复对PCI术后的AMI患者不仅安全，而且能提高其运动能力。
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